You need to post more details about your data, then. PROC IMPORT likely won't help, so you'll need to construct a specialized import - either what Tom posted, or perhaps something simpler. For example. data want; infile "blah.csv" dlm=',' lrecl=1e8 firstobs=2; input a1-a150000 ; run; might work if you don't mind your variable names being a1,a2,...a150000. You probably don't want that, but if your pattern is really easy to work out it might be easier to import it this way and then set up some renames.
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