I am doing analysis of a trial testing satisfaction in VA scale from 0 to 100 in a cross over trial. Patients were assigned to two treatment and followed for 12 months. After the 12 month the treatment was changed and followed for another 12 months. Measures of satisfaction were perfomed at the first week, then at 3 months , 6 months and 12 months (4 times). Distribution was not normal very skewed to the right. I tried some different distributions such as exp and poisson, but residuals are not randomly distributed around zero, specially a the end it positive residuals drasticlly decreases to zero. Independent of the distribution I used , even normal residuals are very similar. Q2 is satisfaction. This is what I am using. proc glimmix plots = all ; class paciente treat (ref = first) time (ref= first); model q2 = treat | time /solution link = log s dist = poisson ; random int /subject = paciente; covtest 'var(paciente) = 0' 0 .; run; Would overdispersion be a problem and a beta binomial be recommended? Thanks so much.
... View more