Would there ever be a reason to not include DIFF=method>? Absolutely yes. All of the methods are designed to control type I error (false positives). However, suppose that it is far more important to control type ii error (false negative rate) in whatever field you are working. Then the unadjusted values give a greater ability to declare a difference significant. As an example, suppose you are working on a safety study for a new drug. In that study, it would be much more important to detect a true difference to protect you from declaring the drug "safe" when in fact it causes some change that may indicate a potential safety concern.   SteveDenham ... View more