In OS table, we have the survival rate at each time point and the confidence interval of each of the two arms, but now we want to see the confidence interval in the survival rate difference. How to calculate the CI of the survival rate difference between two arms, say 5-year OS rate difference CI? Thank you very much!
John
A bit more information would help. Which survival analysis PROC are you using? All of them support a TEST statement, and most support the LSMEANS and LSMESTIMATE statement.
SteveDenham
You might be able to get what you want by doing a restricted mean analysis. Here is a link to an example:
Depending on which level of SAS/STAT you have, you could consider moving to PROC RMSTREG, which has an LSMEANS statement. If it supports the DIFF and CL option, and especially the AT= option, you are in good shape. See this example for a first step:
https://documentation.sas.com/doc/en/statug/15.2/statug_rmstreg_examples02.htm
and this for a more complete analysis
https://documentation.sas.com/doc/en/statug/15.2/statug_rmstreg_examples03.htm
SteveDenham.
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