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Thuva
Calcite | Level 5

I am trying to run an unadjusted model with a categorical variable. The survival model is a shared frailty model with recurrent events. What I need is an overall hazard ratio and 95% CI for the categorical variable (across all individuals), however I am getting a hazard ratio for each individual. 

 

The categorical variables I am interested in are all binary (0=no history disease, 1=yes history of disease), can I just remove the CLASS statement and add them as a continuous variable in the model?

 

My code:

proc phreg data=final_survival_export covs(aggregate) covm; 
class pt_id /*need this to specify ID variable for random effect*/
         prev_corticosteroids (ref='0'); /*character variable of interest*/
model (visit0 visit1)*rs(0)= prev_corticosteroids/rl;
random pt_id /NOCLPRINT ;
run;

 

 

My output for prev_corticosteroids is per individual, however I would like an aggregate estimate. Any help would be greatly appreciated!! 

SAS Output

Parameter   DF Parameter
Estimate
Standard
Error
Chi-Square Pr > ChiSq Hazard
Ratio
Label
prev_corticosteroids 1 1 0.13427 0.08226 2.6640 0.1026 1.144 prev_corticosteroids 1
prev_corticosteroids 2 1 0.57236 0.37623 2.3144 0.1282 1.772 prev_corticosteroids 2
prev_corticosteroids 3 1 0.75211 0.29420 6.5356 0.0106 2.121 prev_corticosteroids 3
prev_corticosteroids 4 1 0.70392 0.45005 2.4464 0.1178 2.022 prev_corticosteroids 4
prev_corticosteroids 5 1 0.68733 0.42074 2.6688 0.1023 1.988 prev_corticosteroids 5
prev_corticosteroids 6 1 0.65960 0.54052 1.4891 0.2224 1.934 prev_corticosteroids 6
prev_corticosteroids 7 1 0.64128 0.76435 0.7039 0.4015 1.899 prev_corticosteroids 7
prev_corticosteroids 8 1 0.62440 1.06027 0.3468 0.5559 1.867 prev_corticosteroids 8
prev_corticosteroids 9 1 0.66906 0.74098 0.8153 0.3666 1.952 prev_corticosteroids 9
prev_corticosteroids 11 1 0.60798 0.73777 0.6791 0.4099 1.837 prev_corticosteroids 11
prev_corticosteroids 12 1 0.59177 0.73702 0.6447 0.4220 1.807 prev_corticosteroids 12
prev_corticosteroids 13 1 0.69821 0.73636 0.8991 0.3430 2.010 prev_corticosteroids 13
prev_corticosteroids 14 1 0.61152 0.60854 1.0098 0.3149 1.843 prev_corticosteroids 14
prev_corticosteroids 15 1 0.61313 1.03611 0.3502 0.5540 1.846 prev_corticosteroids 15
prev_corticosteroids 18 1 0.62734 1.03652 0.3663 0.5450 1.873 prev_corticosteroids 18
prev_corticosteroids 19 1 0.62636 1.04223 0.3612 0.5479 1.871 prev_corticosteroids 19
prev_corticosteroids 24 1 0.64995 1.02797 0.3998 0.5272 1.915 prev_corticosteroids 24
prev_corticosteroids 29 1 0.66863 1.02493 0.4256 0.5142 1.952 prev_corticosteroids 29
1 ACCEPTED SOLUTION

Accepted Solutions
JacobSimonsen
Barite | Level 11

when all your covariates are binary (0,1) variables, then you can add them as continous variables. The estimates will show diffrence between the "1" and "0".

 

You can also use the class variable, as you already did. So cant see what you do wrong. Are yo sure that the prev_corticosteroids is binary. For me it looks like it contains the number of previous events in the recurrent event model.

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3 REPLIES 3
Reeza
Super User
I’m not familiar with that particular model, but did you try a HazardRatio statement?
JacobSimonsen
Barite | Level 11

when all your covariates are binary (0,1) variables, then you can add them as continous variables. The estimates will show diffrence between the "1" and "0".

 

You can also use the class variable, as you already did. So cant see what you do wrong. Are yo sure that the prev_corticosteroids is binary. For me it looks like it contains the number of previous events in the recurrent event model.

Thuva
Calcite | Level 5

Can't believe I missed that! You are absolutely correct - I had two continuous variables that should not have been classified as categorical variables. Thanks for your help!

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