You are getting an error that your personal proifles (that is sasuser) is not accessible.
When you are using Eguide to a server to a SAS workspace server (or other) this is quite common behavior.
Whe you are using SAS base on a PC it looks a definiton has been corrupted. It should point to a "My Documents" location. Conforming the Microsoft requirements and settings. The C:\work advice is one of possible ancient times as C: should not be used in that way, closed down. Also for the work there are microsoft guidelines mostly pointing to a local-settings submap (personal) as Windows is Multi-user Multi-process..
Please give more information on your situation.
---->-- ja karman --<-----