Are you relatively modern SAS CI version (6.x), or a very old thick client version (5.x)? Are you connected locally, or do you access it through Citrix or some other form or a virtual desktop or virtual application environment? Do you operate on normal-sized diagrams, or something unusually large-scale?
Can you record a video to show how your problem looks like?
If you observe some major jumps and misalignments, then this is not a typical problem to be reported by SAS CI Users. Something should be wrong on your side, and you should address this with SAS Technical Support.
In SAS CI Studio (at least in version 6.5), nodes can be moved around at 1/6 of a node size increments horizontally, and 1/3 node size vertically (in a kind of invisible grid). It's not exactly pixel-smooth smooth, but sufficient for most users - and most importantly, nodes can be aligned (either horizontally or vertically) with no issue according to this grid.
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Dmitriy Alergant, Tier One Analytics