I have an GLM and a treament variable given to the patient in a factorial fashion coded in the following manner 1-control 2-oral drug A 3-inhaler B 4-drug A and B togther   My outcome variable is the weekly number of puffs of albuterol taken for the patient's asthma.   I need to test whether the treatment effect, which is significant in my model, can be attributed entirely to the inhaler B. Can someone help me in how I might test this in SAS? Would it be some sort of contrast statement? Thanks all. ... View more

Hello,   I have a dataset with a continuous outcome variable and 3 treatments (1 of which is placebo). I have about 60 observations in my dataset; 60 subjects each of which got 1 treatment and was measured once - the dataset is balanced but measurements were taken in blocks of days but only 2 measurements were taken each day (incomplete blocks?). I need to include the block in  my model as a random effect. I am trying to get the effect of the drug and im running a proc mixed with a random block effect, but i am not getting an anova table and am getting an error that the "Estimated G matrix is not positive definite." Can anyone tell me what I am doing wrong? Thank you. ... View more