Hello, all. I have a two way ANOVA testing the effects of Fungicide and (fungal) Isolate on a Log10EC50 response value (EC50 being the effective chemical concentration that inhibits growth halfway between a minimum and maximum response). I know that my groups of Fungicide*Isolate have very heterogeneous variance (variances range from 0.00073 to 0.87599), and I am trying to fit the model with hetereogeneous variance using the following code. ANOVA Code PROC mixed data=IMPORT;
TITLE3 "ANOVA Comparing LogEC50's, group=Isolate*Fungicide";
class Trial Fungicide Plate Isolate;
model LogEC50 = Fungicide|Isolate / ddfm=KR outp=outH;
Random Plate(Trial) / group=Fungicide*Isolate;
run; I am receiving a memory error. I have a large dataset (over 2,800 observations - the attached PDF shows Class Level Information; there will be about 390 groups that need to be fitted for heterogeneous variance). I have included the fullstimer option to aid in diagnosis. LOG ERROR: The SAS System stopped processing this step because of insufficient memory.
NOTE: The PROCEDURE MIXED printed pages 4-5.
NOTE: PROCEDURE MIXED used (Total process time):
real time 0.13 seconds
user cpu time 0.06 seconds
system cpu time 0.07 seconds
memory 5162.28k
OS Memory 36272.00k
Timestamp 02/25/2016 04:02:39 AM
Step Count 31 Switch Count 223
Page Faults 0
Page Reclaims 695
Page Swaps 0
Voluntary Context Switches 898
Involuntary Context Switches 719
Block Input Operations 0
Block Output Operations 40464 I am looking for a way to conduct the analysis with heterogeneous variance, or suggestions on perhaps transformations to assist with heterogeneity problems? I am running the code through SAS University Edition/SAS Studio, so I recognize that there may be memory problems associated with this platform? I have access to SAS 9.4 on library computers but a different memory error appears there (see below) that I cannot fix due to lacking administrator privileges to apply the hot fix. ERROR: Integer overflow on computing amount of memory required.
A request to allocate the memory cannot be honored. Any suggestions would be very welcome. I hope I provided enough detail, but would be more than willing to add any information that would be helpful! Thank you.
... View more
