Hello everyone, I need your urgent help with a mediation analysis I am conducting using the PROC CAUSALMED method in SAS.   Background: My study includes several mediators, several exposures, and several outcome variables. These variables create 165 possible "Exposure-Mediator-Outcome" pathways, and for each pathway, I am running simple mediation models (one predictor and one mediator per model).   Issue: For all the pathways involving the mediator "v004_rawvalue_2019", the "Summary of Effects" table in output only provides the point estimates but does not report the standard errors, confidence intervals, or any other statistics, with a log saying the convergence is questionable. This issue does not occur for other "Exposure-Mediator-Outcome" models, so I’m unsure how to resolve them. I have tried commenting all the covariates out, but still received the same log and output. Please see the output in pic below:   Code and Log:    PROC CAUSALMED DATA = WORK.A DESC; CLASS exposure MARITAL BREASTCANCER_SUBTYPE TUMOR_GRADE / REF=FIRST;  MEDIATOR v004_rawvalue_2019 = exposure;  MODEL outcome = exposure v004_rawvalue_2019 / DIST=BIN LINK=LOGIT; COVAR AGE MARITAL BREASTCANCER_SUBTYPE TUMOR_GRADE;  RUN; WARNING: The covariance matrix for the outcome model is not positive definite. The convergence is questionable. WARNING: The covariance matrix for the mediator model is not positive definite. The convergence is questionable. WARNING: Standard errors are not computed for the effect estimates.   Does anyone know how to deal with this 😿Thank you very much in advance!! ... View more