I can't imagine some error during debugging process. At Enterprise Guide you must press the F5 key at your keyboard. It will open the Data Step Debugger. After this, you should see something like the picture below. The Enterprise Guide compiles your code in real time, during the execution process. The debugger runs your code at the same time that reads your tables and their data. You also can write some conditionals (e.g. if/else) statements to interact with your data using the _N_ and the _ERROR_ for checking something at the code, for example. Anyway, could you post a picture from the error?
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