Hello, Looking for help and some validation on my current procedure. I have two diagnostic tests, Test1 and Test2 that I have calculated sensitivity, specificity, NPV, PPV and F1 scores for. I want to determine if one test is superior on each of these parameters. My data is given as 1 if test is positive, and 0 if test is negative. Same for disease. For sensitvity and specficity, so far I have used McNemars following this method: https://onlinecourses.science.psu.edu/stat509/node/152/ For the specficty i made sure that the first row and first column had the test negative but am getting the same P value. For PPV, and NPV I have found this macro: https://support.sas.com/resources/papers/proceedings15/2141-2015.pdf But I can't seem to get the macro to work as it references "t" and I can't seem to figure out where the t is coming from. . No clue where to start for the F1, but I've read a paper that refereces using McNemars also but not sure how that would work. Any help is greatly appreciated!
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