Hi, I am unfamiliar with SAS and trying to calculate the incremental area under the curve. I normally use SPSS and have been unable to find syntax to do so using that program. I did, however, find the below guide that offers syntax to calculate AUC by three different approaches here: https://www.lexjansen.com/wuss/2004/posters/c_post_the_sas_calculations_.pdf The method I am particularly keen to use is the "positive incremental area under the curve" one. I have downloaded SAS and am managing to successfully calculate the total AUC using the example data and code in the link above. I am, however, struggling to get it to work using the code required for the alternative methods such as iAUC I'd be very grateful if anyone could paste the code as it should be entered into SAS to determine the iAUC. I have also pasted a sample of the data from my study (left column is time in minutes, right column is glucose concentration in response to a standardised meal) that is representative of what I'd like to calculate iAUC on if helpful: 0 4.746 15 6.688 30 7.053 45 6.953 60 5.483 90 4.654 120 4.532 180 4.455 240 4.393 300 4.295 360 4.621 Any pointers would be much appreciated and apologies if this is very basic. BW, Niall
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