Okay, the final, final answer and solution from Martin @sas.support: When invoking SAS, if you get notes such as the following: NOTE: Unable to open SASUSER.REGSTRY. WORK.REGSTRY will be opened instead. NOTE: All registry changes will be lost at the end of the session. NOTE: Unable to open SASUSER.PROFILE. WORK.PROFILE will be opened instead. NOTE: All profile changes will be lost at the end of the session. The cause is typically due to either corrupt profile files in SASUSER or incompatible profile files in SASUSER. For example, if you happen to be running the 64-bit version of SAS but you are using old profile files created with the 32-bit version of SAS (perhaps via a previous install), then you will get the notes above. In this case, your only option is to follow the steps I sent in my previous email to rename all of the files in SASUSER (so when starting up a new SAS session, SAS will recreate the profile files from scratch). Also note that you will get the note statements above when invoking multiple SAS sessions on the same Windows machine (since only the very first invocation of SAS will have write/update access to SASUSER). However, if you constantly get the notes above when only invoking a single SAS session, then you will have to rename all of the profile files in SASUSER. submit the following statements to SAS: proc options option=sasuser; run; Look in the SAS log and jot down the Windows directory that SASUSER points to. Then, exit SAS. Using Windows Explorer, open the Windows directory that SASUSER points to. In this directory, locate the following files: profile.sas7bcat profile2.sas7bcat profbak.sas7bcat templat.sas7bitm regstry.sas7bitm If any of the files above exist in this directory, rename them to: profile.old profile2.old profbak.old templat.old regstry.old Then, restart SAS and let me know if this does not resolve the original issue.
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