Below are the details. Please let me know if you need more info. There are 200 subject in study with 100 and 100 treated patients in TRT1 and TRT2, respectively, Objective response rate (ORR) can be estimated with a maximum standard error of 0.041 and 0.071, respectively. Assuming a beta (0.5, 0.5) prior: •TRT1: if 44 responders (out of 100 patients, ORR of 44%) are observed, the posterior probability of a true ORR >=40% will be >=0.80 (0.841). •TRT2: if 46 responders (out of 100 patients, ORR of 46%) are observed, the posterior probability of a true ORR >=40% will be >=0.80 (0.807).
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