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antor82
Obsidian | Level 7

Hi all

 

is there a macro/code that mimics in SAS what pROC and bootLR do in R?

 

my aim is to calculate bootstrap threshold, sensitivity, specificity, LT+ and LR- along with 95% CI

 

Tks!

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PaigeMiller
Diamond | Level 26

@antor82 wrote:

is there a macro/code that mimics in SAS what pROC and bootLR do in R?

 


What do pROC and bootLR do?

--
Paige Miller
antor82
Obsidian | Level 7
bootLR Computes the (positive/negative) likelihood ratio with appropriate, bootstrapped confidence intervals

pROC computes threshold sensitivity and specificity for a given value with appropriate, bootstrapped confidence intervals
PaigeMiller
Diamond | Level 26

Normally, a likelihood ratio is computed to test to see if a statistic is significantly different than some quantity ... what statistic is being tested, and in what context?

 

Normally, bootstrap confidence intervals are computed to see some measure of variability of a particular statistic ... what statistic is being tested, and in what context?

--
Paige Miller
antor82
Obsidian | Level 7
I’m testing if a new parameter is predictive of an outcome.
My sample size is small (60 patients).
Other authors did the same and provided AUC, cut-off (with corresponding sensibility, specificity, LR+ and -) calculated after bootstrapping
PaigeMiller
Diamond | Level 26

I’m testing if a new parameter is predictive of an outcome.

 

Some sort of regression??? A decision tree??? A Neural Network??? What is the exact type of model?

 

Other authors did the same and provided AUC, cut-off (with corresponding sensibility, specificity, LR+ and -) calculated after bootstrapping

 

Logistic regression?? Decision tree?? Neural Network?? Other???

 

--
Paige Miller
antor82
Obsidian | Level 7
Logistic regression
PaigeMiller
Diamond | Level 26

@Rick_SAS has written the definitive guide to bootstrapping in SAS

https://blogs.sas.com/content/iml/2018/12/12/essential-guide-bootstrapping-sas.html

 

--
Paige Miller
antor82
Obsidian | Level 7
Tks!

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