Lund Test for Outlier Analysis in Ratios

[ahmedazab88]

Dear all

Can you help me to make Lund Test for Outlier Analysis in Ratios to be used in bioequivalence studies, var AUC & Cmax

For Example:

Obs	Subject	Ratio for AUCT	Ratio for AUC00	Ratio for Cmax	Lund	Prescott	Outlier
1	1	1.40988	1.31543	0.91176	2.73085	3.27961	No
2	2	0.95385	0.94783	0.96886	1.00064	3.27961	No

Best Regards

Ahmed

[ahmedazab88]

I found this code

Proc glm outstat=Lund;

class Subject Treat Seq Period;

MODEL Log_AUCT Log_AUCinf Log_Cmax=seq subject(seq) Treat period;

lsmeans Treat/stderr; Estimate 'test-ref' Treat -1 1;

Output out=Lund P=PRED R=RESID stdr=eresid STUDENT=STDRESID;

Best Regards

Ahmed