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Nancych
Fluorite | Level 6

Hi,

 

I am running into an issue for a subgroup analysis (by sex). The model converged, but the Hazard ratio from PHREG is extremely huge. you might see from below, there is no event for category of female. Is there anyway we could deal with it, such as correction? how about the HR and CIs for male, is that still valid? I appreciate any suggestions in such situation.

 

 

 

Treatment

Placebo

Female

 

 

   Number assessed

20

14

  Censored

9

14

  Events

10

0

  Hazard Ratio (CI)

1267890 (0.000,-)

 

Male

 

 

   Number assessed

20

19

  Censored

14

14

  Events

6

5

  Hazard Ratio (CI)

0.69 ( 0.23; 2.06)

 

 

proc phreg data = XXX;

   class trt sex;

   model aval*cnsr(1) = trt sex trt*sex/ties = efron rl alpha=0.05 ;

   HAZARDRATIO trt/diff=ref;

run;

 

Thank you,

Lily

1 REPLY 1
Nancych
Fluorite | Level 6

anyone can help?

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