I have the following data:
data have;
input
ID Dose Days Event Age;
datalines;
1 1 10 1 35
2 1 40 0 35
2 2 55 0 25
2 3 23 1 67
3 1 20 0 34
3 2 35 0 34
3 3 15 1 25
4 1 40 0 53
4 2 55 1 53
;
run;
Here, dose variable changes with time. Days is the duration an individual stays alive (or die at the end of period) at a certain dose level. If the individual does not die, the dose is increased (1 to 2 or 2 to 3). Event variable shows when an event (death = 1) occurred. This can be at the end of any dosing period.
Is there any way to run a cox model where dose is the exposure of interest and age is a covariate?