Hi,
Am new to this topic. Suppose I have a vaccine data and am asked to analyze the efficacy. The data was initially analyze for efficacy using Kaplan–Meier estimator and I want to reanalyze the data using another method e.g. cox regression. Would cox regression be appropriate? what other methods can I attempt?
I aim to demonstrate that new treatment is better (superior) than control, my control is placebo. So i think this should be a superiority trial of vaccine vs placebo not active treatment.
How can i get helpful sas code as resources? Thanks
Is your data censored ?
proc lifereg or proc phreg do survival analysis, that need your data is censored .
If not, you could try other normal model like : proc freq or proc logistic or proc ttest or proc npar1way or proc glm .....
Yes, the data is censored. What other analytic method apart from cox regression can I attempt?
If you have access to SAS/ETS, you might look at PROC QLIM for a variety of tobit analyses.
Also, you may wish to look at this paper, as for a vaccine trial you will likely have competing events:
SteveDenham
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