Splitting the file won't probably help you, since SAS would probably read the data as fast as your splitting program would.
If you plan just to do this once, I would say don't bother about performance.
If you plan to import this file on a regularly basis, you might need to design (simple) a ETL flow, where you might optimize by just import changed data in some way.
I don't think that there are any options that will affect the performance that much.
SAS is considered very fast for importing flat files, even compared with various bulk-loaders available with the competition.
/Linus
Data never sleeps