@RajasekharReddy wrote:
.....
PARTN=1 PARTTXT=Part 1 Dose Escalation TRTP=3 mg/kg PARAM=Carboxy-Dabrafenib PARAMCD=2298683 AVISITN=50 AVISIT=WEEK 1 DAY 1
ATPTNUM=70 ATPT=4 HOURS POST DOSE _TYPE_=0 _FREQ_=1 n1=1 nc=1 mean1=2968.26 gmean=2968.26 max1=2968.26 min1=2968.26 sd= gsd=
med=2968.26 CV1= gmean1= gcv= _ERROR_=1 _N_=3
NOTE: Mathematical operations could not be performed at the following places. The results of the operations have been set to
missing
values.
Looks like a value for gmean of 2968.26 is above the limit.
From the documentation:
The result is limited by the maximum value of a floating-point value on the computer.
https://go.documentation.sas.com/?docsetId=lefunctionsref&docsetTarget=n0ocutx9jgosdln17xg1z75jmkbv....
28 data test;
29 do gmean=1,2,.,2968.26;
30 if nmiss(gmean)=0 then gmean1=exp(gmean);
31 end;
32 stop;
33 run;
NOTE: Invalid argument to function EXP(2968.26) at line 30 column 35.
gmean=2968.26 gmean1=. _ERROR_=1 _N_=1
NOTE: Mathematical operations could not be performed at the following places. The results of the operations have been set to
missing values.
Just by trying in a SAS9.4 environment it appears the limit is somewhere below a value of 710.
28 data test;
29 do gmean=1 to 3000;
30 if nmiss(gmean)=0 then gmean1=exp(gmean);
31 end;
32 stop;
33 run;
NOTE: Invalid argument to function EXP(710) at line 30 column 35.
NOTE: Invalid argument to function EXP(711) at line 30 column 35.
