More clearly stated, z/OS (DFSMS-managed, striped datasets) compression is not supported except for "SAS sequential-access formatted" data sets (tape or DASD allocated). And so with your typical SAS z/OS (IBM mainframe environment) direct-access bound data libraries, suggest using COMPRESS=YES for large-observation/wide-columns datasets, as mentioned by Peter.C in his prior post, where you stand to benefit up to 50% or more on space-savings, again presuming you are not CPU-limited. Also, also consider a more optimum BLKSIZE setting in SAS z/OS rather than the SAS system default of 6144.
If using SAS on z/OS (the OS platform for SAS was not stated in the original post), suggest the OP review the SAS Companion documentation - in fact, the "performance topic" for any OS platform is a reasonable reading topic in my perspective.
Scott Barry
SBBWorks, Inc.