Dear All,
I got an RTF SAS output file From someone I don't know (i.e. saved and opened as a word document) and when I right clicked the file and opened the "source Code", it was an HTML file not RTF one!!!. When I opened the file with GOOGLE CHROME it was opened with the same formatting as with the RTF. I mean the source code of the file is HTML and it can be opened with WORD and any browser.
For me I am saving my file using this ODS code to save the output " ods html file= "C:\Users\Administrator\Desktop\XXX.html
ods html close;" . This will open the file as HTML file. I want to open it with Microsoft word and gives me the same format as HTML like the file I received.
Is there a Syntax to use in the sourcde code that can open the file as HTML and WORD (Word format like HTML)?.
Thanks.
Yours,
M.Yehia
I took your two blobs of HTML, saved them to files, and then attached them as output1.txt and output2.txt. As someone mentioned earlier, this is the preferred way to share a large amount of data.
The forum software wouldn't let me attach .htm files (!!) so download the files and rename them to output1.htm and output2.htm.
The output1.htm file was created using the HTML3 destination and the "Default" style supplied by SAS.
The output2.htm file was created using the HTML4 destination and a style that is similar to "Default". I see some differences but I'm unable to tell if they are due to being created by different versions of SAS, or if someone modified the "Default" style and used it here.
Open both files using a Web browser and you will see that they have a similar, but different appearance.
Now open both files using Microsoft Word. The two files look very different when rendered by Microsoft Word. The output1.htm file looks close to what you see in the Web browser. The HTML for the output2.htm file uses CSS to control the appearance, and apparently Microsoft Word does not handle the CSS very well.
Here is some sample code that illustrates how the files might have been created:
ods html3 file='C:\temp\vince_output1.htm' style=Default;
proc means data=sashelp.class n mean median min max range;
class sex;
var age height weight;
run; quit;
ods html3 close;
ods html4 file='C:\temp\vince_output2.htm' style=Default;
proc means data=sashelp.class n mean median min max range;
class sex;
var age height weight;
run; quit;
ods html4 close;
Vince DelGobbo
SAS R&D
Try Change its suffix name.
"C:\Users\Administrator\Desktop\XXX.html
-->
"C:\Users\Administrator\Desktop\XXX.rtf
or use other ods destination like:
ods tagsets.msoffice2k ...........
ods tagsets.rtf................
ods tagsets.excelxp.........
I will post here the 2 codes and you will understand what I mean:
the file "1" is the right code that I received and can be saved and opened as both html or rtf:
[Edit: Long code removed and attached as files in this message from Vince]
the file "2" is my code that it is opened as HTML and if opened as RTF it will be of totally different formatting:
<!DOCTYPE html PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN">
<html>
<head>
<meta http-equiv="Content-type" content="text/html; charset=windows-1252">
<title>SAS Output</title>
</HEAD>
<BODY onload="startup()" onunload="shutdown()" vlink="#004488" link="#0066AA" leftmargin=8 rightmargin=8 bgcolor="#E0E0E0">
<SCRIPT LANGUAGE="JavaScript">
function startup(){ }
function shutdown(){ }
</SCRIPT>
<style type="text/css">
<!--
.ContentTitle
{
font-family: Times Roman;
font-size: 12pt;
font-weight: bold;
font-style: italic;
color: #002288;
}
.Output
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #F0F0F0;
border-width: 1px;
border-color: #000000;
}
.HeaderEmphasis
{
font-family: Times Roman;
font-size: 12pt;
font-weight: bold;
font-style: italic;
color: #0033AA;
background-color: #B0B0B0;
}
.NoteContent
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.Graph
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
border-width: 1px;
border-color: #000000;
}
.WarnContentFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.NoteBanner
{
font-family: Verdana;
font-size: 12pt;
font-weight: bold;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.FatalContent
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.DataStrong
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #000000;
background-color: #D3D3D3;
}
.Document
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
a:link {
color:#0066AA
}
a:visited {
color:#004488
}
a:active {
color:#004488
}
.BeforeCaption
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #000000;
background-color: #E0E0E0;
}
.ContentsDate
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
width: 100%;
}
.Pages
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
margin-left: 8px;
margin-right: 8px;
list-style-type: decimal;
}
.TitlesAndFooters
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: italic;
color: #002288;
background-color: #E0E0E0;
}
.IndexProcName
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
list-style-type: decimal;
}
.ProcTitle
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: italic;
color: #002288;
background-color: #E0E0E0;
}
.Table
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #F0F0F0;
border-width: 4pt;
border-color: #000000;
}
.top_stacked_value
{
padding-bottom: 1px;
}
.middle_stacked_value
{
padding-top: 1px;
padding-bottom: 1px;
}
.bottom_stacked_value
{
padding-top: 1px;
}
.IndexAction
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
margin-left: 6pt;
list-style-type: NONE;
}
.Data
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #000000;
background-color: #D3D3D3;
}
.FooterEmpty
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.SysTitleAndFooterContainer
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
border-width: 0;
width: 100%;
}
.Container
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.RowFooterEmpty
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.ExtendedPage
{
font-family: Times Roman;
font-size: 12pt;
font-weight: bold;
font-style: italic;
color: #002288;
background-color: #E0E0E0;
border-width: 1pt;
text-align: center;
}
.RowFooterEmphasis
{
font-family: Times Roman;
font-size: 12pt;
font-weight: bold;
font-style: italic;
color: #0033AA;
background-color: #B0B0B0;
}
.FooterFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.RowFooterFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.Caption
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #000000;
background-color: #E0E0E0;
}
.Index
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.RowFooterStrongFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.ContentFolder
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
list-style-type: NONE;
}
.Date
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
width: 100%;
}
.WarnBanner
{
font-family: Verdana;
font-size: 12pt;
font-weight: bold;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.Note
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.HeaderStrongFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.NoteContentFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.DataEmphasisFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: italic;
color: #000000;
background-color: #D3D3D3;
}
.IndexTitle
{
font-family: Times Roman;
font-size: 12pt;
font-weight: bold;
font-style: italic;
color: #002288;
}
.Byline
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.FatalBanner
{
font-family: Verdana;
font-size: 12pt;
font-weight: bold;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.ProcTitleFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: bold;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.ByContentFolder
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
list-style-type: NONE;
}
.PagesProcLabel
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
list-style-type: decimal;
}
.RowFooterEmphasisFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: italic;
color: #0033AA;
background-color: #B0B0B0;
}
.WarnContent
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.Header
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.RowHeaderFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.DataEmpty
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #000000;
background-color: #D3D3D3;
}
.Body
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
margin-left: 8px;
margin-right: 8px;
}
.Cell
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.PageNo
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
text-align: right;
vertical-align: top;
}
.RowHeaderEmpty
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.HeaderFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.ContentItem
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
list-style-type: NONE;
}
.Batch
{
font-family: Courier;
font-size: 6.7pt;
font-weight: normal;
font-style: normal;
color: #000000;
background-color: #D3D3D3;
border-width: 1px;
border-color: #000000;
}
.PagesProcName
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
list-style-type: decimal;
}
.PagesTitle
{
font-family: Times Roman;
font-size: 12pt;
font-weight: bold;
font-style: italic;
color: #002288;
}
.ContentProcLabel
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
list-style-type: decimal;
}
.PagesDate
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
width: 100%;
}
.Frame
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.HeaderEmpty
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.FooterStrong
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.FooterEmphasis
{
font-family: Times Roman;
font-size: 12pt;
font-weight: bold;
font-style: italic;
color: #0033AA;
background-color: #B0B0B0;
}
.ErrorContent
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.DataFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: normal;
color: #000000;
background-color: #D3D3D3;
}
.HeaderStrong
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.DataEmphasis
{
font-family: Times Roman;
font-size: 12pt;
font-weight: bold;
font-style: italic;
color: #000000;
background-color: #D3D3D3;
}
.TitleAndNoteContainer
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
border-width: 0;
width: 100%;
}
.BylineContainer
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
border-width: 0;
width: 100%;
}
.FatalContentFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.Contents
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
margin-left: 8px;
margin-right: 8px;
list-style-type: decimal;
}
.RowFooter
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.IndexItem
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
margin-left: 6pt;
list-style-type: NONE;
}
.BodyDate
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
width: 100%;
text-align: right;
vertical-align: top;
}
.FooterEmphasisFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: italic;
color: #0033AA;
background-color: #B0B0B0;
}
.RowFooterStrong
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.HeadersAndFooters
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.RowHeaderStrong
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.RowHeaderEmphasisFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: italic;
color: #0033AA;
background-color: #B0B0B0;
}
.ErrorBanner
{
font-family: Verdana;
font-size: 12pt;
font-weight: bold;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.ContentProcName
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
list-style-type: decimal;
}
.UserText
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.PagesItem
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
list-style-type: NONE;
}
.RowHeader
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.FooterStrongFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.AfterCaption
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #000000;
background-color: #E0E0E0;
}
.RowHeaderStrongFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.SystemFooter
{
font-family: Verdana;
font-size: 16pt;
font-weight: bold;
font-style: italic;
color: #002288;
background-color: #E0E0E0;
}
.RowHeaderEmphasis
{
font-family: Times Roman;
font-size: 12pt;
font-weight: bold;
font-style: italic;
color: #0033AA;
background-color: #B0B0B0;
}
.Footer
{
font-family: Verdana;
font-size: 14pt;
font-weight: bold;
font-style: normal;
color: #0033AA;
background-color: #B0B0B0;
}
.FolderAction
{
font-family: Verdana;
font-size: 12pt;
font-weight: normal;
font-style: normal;
color: #0033AA;
margin-left: 6pt;
list-style-type: NONE;
}
.HeaderEmphasisFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: italic;
color: #0033AA;
background-color: #B0B0B0;
}
.SystemTitle
{
font-family: Verdana;
font-size: 16pt;
font-weight: bold;
font-style: italic;
color: #002288;
background-color: #E0E0E0;
}
.ErrorContentFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: normal;
font-style: normal;
color: #002288;
background-color: #E0E0E0;
}
.DataStrongFixed
{
font-family: Courier;
font-size: 9pt;
font-weight: bold;
font-style: normal;
color: #000000;
background-color: #D3D3D3;
}
.l {text-align: left }
.c {text-align: center }
.r {text-align: right }
.d {text-align: "." }
.t {vertical-align: top }
.m {vertical-align: middle }
.b {vertical-align: bottom }
TD, TH {vertical-align: top }
.stacked_cell{padding: 0 }
-->
</style>
<script language="javascript" type="text/javascript">
<!--
function startup(){
}
function shutdown(){
}
//-->
</script>
<noscript></noscript>
</head>
<body onload="startup()" onunload="shutdown()" class="Body">
<script language="javascript" type="text/javascript">
<!--
var _info = navigator.userAgent
var _ie = (_info.indexOf("MSIE") > 0
&& _info.indexOf("Win") > 0
&& _info.indexOf("Windows 3.1") < 0);
//-->
</script>
<noscript></noscript>
<div class="branch">
<a name="IDX"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Descriptive statistics for pharmacokinetics parameters of AUC0-t AUC0-inf Cmax</td>
</tr>
</table><br>
<div class="c ProcTitle">The MEANS Procedure</div>
<p>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Means: Summary statistics">
<colgroup>
<col>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="r b Header" scope="col">Treat</th>
<th class="l b Header" scope="col">Variable</th>
<th class="r b Header" scope="col">N</th>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Median</th>
<th class="r b Header" scope="col">Minimum</th>
<th class="r b Header" scope="col">Maximum</th>
<th class="r b Header" scope="col">Range</th>
<th class="r b Header" scope="col">Std Dev</th>
<th class="r b Header" scope="col">Coeff of Variation</th>
</tr>
</thead>
<tbody>
<tr>
<th class="r t Data">1</th>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<th class="l Data top_stacked_value">AUC0_T</th>
</tr>
<tr>
<th class="l Data middle_stacked_value">AUC0_INF</th>
</tr>
<tr>
<th class="l Data bottom_stacked_value">Cmax</th>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">30</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">30</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">30</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">2.997</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">3.029</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">1.205</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">3.071</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">3.088</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">1.235</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">2.416</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">2.466</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">0.581</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">3.317</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">3.330</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">1.631</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">0.901</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">0.864</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">1.051</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">0.251</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">0.242</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">0.246</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">8.358</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">7.994</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">20.446</td>
</tr>
</table></td>
</tr>
<tr>
<th class="r t Data">2</th>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<th class="l Data top_stacked_value">AUC0_T</th>
</tr>
<tr>
<th class="l Data middle_stacked_value">AUC0_INF</th>
</tr>
<tr>
<th class="l Data bottom_stacked_value">Cmax</th>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">30</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">30</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">30</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">2.994</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">3.023</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">1.146</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">3.057</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">3.092</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">1.212</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">2.247</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">2.271</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">0.475</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">3.433</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">3.441</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">1.495</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">1.186</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">1.170</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">1.020</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">0.258</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">0.250</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">0.233</td>
</tr>
</table></td>
<td class="stacked_cell Data"><table width="100%" border="0" cellpadding="10pt" cellspacing="0">
<tr>
<td class="r Data top_stacked_value">8.612</td>
</tr>
<tr>
<td class="r Data middle_stacked_value">8.281</td>
</tr>
<tr>
<td class="r Data bottom_stacked_value">20.303</td>
</tr>
</table></td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
</div>
<div class="branch">
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX1"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Levene test for homogeneity of variance AUC0-t AUC0-inf Cmax</td>
</tr>
</table><br>
<div class="c ProcTitle">The GLM Procedure</div>
<p>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Levene's HoV Test">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="6" scope="colgroup">Levene's Test for Homogeneity of AUC0_T Variance<br>ANOVA of Absolute Deviations from Group Means</th>
</tr>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Sum of Squares</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">1</td>
<td class="r Data">0.000581</td>
<td class="r Data">0.000581</td>
<td class="r Data">0.02</td>
<td class="r Data">0.8807</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Error</th>
<td class="r Data">58</td>
<td class="r Data">1.4828</td>
<td class="r Data">0.0256</td>
<td class="r Data"> </td>
<td class="r Data"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX2"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Levene's HoV Test">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="6" scope="colgroup">Levene's Test for Homogeneity of AUC0_INF Variance<br>ANOVA of Absolute Deviations from Group Means</th>
</tr>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Sum of Squares</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">1</td>
<td class="r Data">0.000482</td>
<td class="r Data">0.000482</td>
<td class="r Data">0.02</td>
<td class="r Data">0.8893</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Error</th>
<td class="r Data">58</td>
<td class="r Data">1.4293</td>
<td class="r Data">0.0246</td>
<td class="r Data"> </td>
<td class="r Data"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX3"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Levene's HoV Test">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="6" scope="colgroup">Levene's Test for Homogeneity of Cmax Variance<br>ANOVA of Absolute Deviations from Group Means</th>
</tr>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Sum of Squares</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">1</td>
<td class="r Data">0.000068</td>
<td class="r Data">0.000068</td>
<td class="r Data">0.00</td>
<td class="r Data">0.9583</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Error</th>
<td class="r Data">58</td>
<td class="r Data">1.4393</td>
<td class="r Data">0.0248</td>
<td class="r Data"> </td>
<td class="r Data"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX4"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Levene test for homogeneity of variance AUC0-t AUC0-inf Cmax</td>
</tr>
</table><br>
<div class="c ProcTitle">The GLM Procedure</div>
<p>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Means">
<colgroup>
<col>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" rowspan="2" scope="col">Level of<br>Treat</th>
<th class="r b Header" rowspan="2" scope="col">N</th>
<th class="c b Header" colspan="2" scope="colgroup">AUC0_T</th>
<th class="c b Header" colspan="2" scope="colgroup">AUC0_INF</th>
<th class="c b Header" colspan="2" scope="colgroup">Cmax</th>
</tr>
<tr>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">1</th>
<th class="r Data">30</th>
<td class="r Data">2.99721767</td>
<td class="r Data">0.25051324</td>
<td class="r Data">3.02924723</td>
<td class="r Data">0.24216113</td>
<td class="r Data">1.20483802</td>
<td class="r Data">0.24634523</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">2</th>
<th class="r Data">30</th>
<td class="r Data">2.99436099</td>
<td class="r Data">0.25788211</td>
<td class="r Data">3.02310097</td>
<td class="r Data">0.25033165</td>
<td class="r Data">1.14613410</td>
<td class="r Data">0.23270268</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
</div>
<div class="branch">
</div>
<div class="branch">
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX5"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Normality test for AUC0-T AUC0-inf Cmax</td>
</tr>
</table><br>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Print: Data Set WORK.SHAPIRO">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c Header" scope="col">Obs</th>
<th class="l Header" scope="col">PK</th>
<th class="c Header" scope="col">Treat</th>
<th class="c Header" scope="col">Test</th>
<th class="c Header" scope="col">Statistics</th>
<th class="c Header" scope="col">pValue</th>
<th class="l Header" scope="col">Result</th>
</tr>
</thead>
<tbody>
<tr>
<th class="r RowHeader" scope="row">1</th>
<td class="l Data">AUC0_T</td>
<td class="l Data">1</td>
<td class="l Data">Shapiro-Wilk</td>
<td class="r Data">0.897</td>
<td class="r Data">0.007</td>
<td class="l Data">NonNormal</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">2</th>
<td class="l Data">AUC0_T</td>
<td class="l Data">2</td>
<td class="l Data">Shapiro-Wilk</td>
<td class="r Data">0.914</td>
<td class="r Data">0.018</td>
<td class="l Data">NonNormal</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">3</th>
<td class="l Data">AUC0_INF</td>
<td class="l Data">1</td>
<td class="l Data">Shapiro-Wilk</td>
<td class="r Data">0.893</td>
<td class="r Data">0.006</td>
<td class="l Data">NonNormal</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">4</th>
<td class="l Data">AUC0_INF</td>
<td class="l Data">2</td>
<td class="l Data">Shapiro-Wilk</td>
<td class="r Data">0.901</td>
<td class="r Data">0.009</td>
<td class="l Data">NonNormal</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">5</th>
<td class="l Data">Cmax</td>
<td class="l Data">1</td>
<td class="l Data">Shapiro-Wilk</td>
<td class="r Data">0.929</td>
<td class="r Data">0.045</td>
<td class="l Data">NonNormal</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">6</th>
<td class="l Data">Cmax</td>
<td class="l Data">2</td>
<td class="l Data">Shapiro-Wilk</td>
<td class="r Data">0.933</td>
<td class="r Data">0.058</td>
<td class="l Data">Normal</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
</div>
<div class="branch">
</div>
<div class="branch">
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX6"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Studentized Residuals Test of Outlier Analysis for AUC0-T AUC0-INF Cmax </td>
</tr>
</table><br>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Print: Data Set WORK.QQQ">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c Header" scope="col">Obs</th>
<th class="c Header" scope="col">subject</th>
<th class="c Header" scope="col">AUCT_RATIO</th>
<th class="c Header" scope="col">AUCINF_RATIO</th>
<th class="c Header" scope="col">Cmax_Ratio</th>
<th class="c Header" scope="col">Residuals</th>
<th class="c Header" scope="col">CookD</th>
<th class="c Header" scope="col">Outlier</th>
</tr>
</thead>
<tbody>
<tr>
<th class="r RowHeader" scope="row"> 1</th>
<td class="r Data"> 1</td>
<td class="r Data">1.1906</td>
<td class="r Data">1.1847</td>
<td class="r Data">1.1588</td>
<td class="r Data"> 0.79223</td>
<td class="r Data">0.04560</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row"> 2</th>
<td class="r Data"> 2</td>
<td class="r Data">0.7304</td>
<td class="r Data">0.7518</td>
<td class="r Data">1.1348</td>
<td class="r Data" nowrap>-0.94455</td>
<td class="r Data">0.05764</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row"> 3</th>
<td class="r Data"> 3</td>
<td class="r Data">0.9553</td>
<td class="r Data">0.9643</td>
<td class="r Data">0.9245</td>
<td class="r Data" nowrap>-0.12068</td>
<td class="r Data">0.00083</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row"> 4</th>
<td class="r Data"> 4</td>
<td class="r Data">0.9499</td>
<td class="r Data">0.9489</td>
<td class="r Data">0.9120</td>
<td class="r Data" nowrap>-0.15508</td>
<td class="r Data">0.00122</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row"> 5</th>
<td class="r Data"> 5</td>
<td class="r Data">0.9097</td>
<td class="r Data">0.9142</td>
<td class="r Data">1.0625</td>
<td class="r Data" nowrap>-0.31663</td>
<td class="r Data">0.00450</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row"> 6</th>
<td class="r Data"> 6</td>
<td class="r Data">0.9835</td>
<td class="r Data">0.9856</td>
<td class="r Data">0.8761</td>
<td class="r Data" nowrap>-0.06117</td>
<td class="r Data">0.00015</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row"> 7</th>
<td class="r Data"> 7</td>
<td class="r Data">1.6950</td>
<td class="r Data">1.6911</td>
<td class="r Data">2.1269</td>
<td class="r Data"> 2.50638</td>
<td class="r Data">0.22008</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row"> 8</th>
<td class="r Data"> 8</td>
<td class="r Data">0.9768</td>
<td class="r Data">0.9804</td>
<td class="r Data">0.9745</td>
<td class="r Data" nowrap>-0.11480</td>
<td class="r Data">0.00041</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row"> 9</th>
<td class="r Data"> 9</td>
<td class="r Data">0.5463</td>
<td class="r Data">0.5619</td>
<td class="r Data">0.6063</td>
<td class="r Data" nowrap>-1.68073</td>
<td class="r Data">0.07768</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">10</th>
<td class="r Data">10</td>
<td class="r Data">1.0068</td>
<td class="r Data">0.9885</td>
<td class="r Data">1.0003</td>
<td class="r Data" nowrap>-0.03601</td>
<td class="r Data">0.00003</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">11</th>
<td class="r Data">11</td>
<td class="r Data">0.8456</td>
<td class="r Data">0.8528</td>
<td class="r Data">0.9886</td>
<td class="r Data" nowrap>-0.62869</td>
<td class="r Data">0.00874</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">12</th>
<td class="r Data">12</td>
<td class="r Data">1.7981</td>
<td class="r Data">1.7540</td>
<td class="r Data">1.7056</td>
<td class="r Data"> 2.76631</td>
<td class="r Data">0.15438</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">13</th>
<td class="r Data">13</td>
<td class="r Data">0.9061</td>
<td class="r Data">0.9036</td>
<td class="r Data">0.9310</td>
<td class="r Data" nowrap>-0.44000</td>
<td class="r Data">0.00363</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">14</th>
<td class="r Data">14</td>
<td class="r Data">0.9982</td>
<td class="r Data">0.9954</td>
<td class="r Data">1.2138</td>
<td class="r Data" nowrap>-0.12553</td>
<td class="r Data">0.00028</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">15</th>
<td class="r Data">15</td>
<td class="r Data">0.9641</td>
<td class="r Data">0.9745</td>
<td class="r Data">1.0317</td>
<td class="r Data" nowrap>-0.26192</td>
<td class="r Data">0.00119</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">16</th>
<td class="r Data">16</td>
<td class="r Data">1.0670</td>
<td class="r Data">1.0652</td>
<td class="r Data">0.9286</td>
<td class="r Data"> 0.09055</td>
<td class="r Data">0.00014</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">17</th>
<td class="r Data">17</td>
<td class="r Data">0.9862</td>
<td class="r Data">0.9867</td>
<td class="r Data">0.8030</td>
<td class="r Data" nowrap>-0.21266</td>
<td class="r Data">0.00080</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">18</th>
<td class="r Data">18</td>
<td class="r Data">0.9983</td>
<td class="r Data">0.9936</td>
<td class="r Data">1.5211</td>
<td class="r Data" nowrap>-0.18439</td>
<td class="r Data">0.00064</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">19</th>
<td class="r Data">19</td>
<td class="r Data">0.4464</td>
<td class="r Data">0.4669</td>
<td class="r Data">0.4569</td>
<td class="r Data" nowrap>-2.17448</td>
<td class="r Data">0.09539</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">20</th>
<td class="r Data">20</td>
<td class="r Data">1.2579</td>
<td class="r Data">1.2326</td>
<td class="r Data">1.2723</td>
<td class="r Data"> 0.71610</td>
<td class="r Data">0.01134</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">21</th>
<td class="r Data">21</td>
<td class="r Data">0.8376</td>
<td class="r Data">0.8313</td>
<td class="r Data">1.1134</td>
<td class="r Data" nowrap>-0.80748</td>
<td class="r Data">0.01600</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">22</th>
<td class="r Data">22</td>
<td class="r Data">0.9628</td>
<td class="r Data">0.9936</td>
<td class="r Data">0.8755</td>
<td class="r Data" nowrap>-0.37347</td>
<td class="r Data">0.00384</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">23</th>
<td class="r Data">23</td>
<td class="r Data">0.9705</td>
<td class="r Data">0.9585</td>
<td class="r Data">1.1134</td>
<td class="r Data" nowrap>-0.36181</td>
<td class="r Data">0.00406</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">24</th>
<td class="r Data">24</td>
<td class="r Data">1.5444</td>
<td class="r Data">1.5285</td>
<td class="r Data">1.5729</td>
<td class="r Data"> 1.70470</td>
<td class="r Data">0.10181</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">25</th>
<td class="r Data">25</td>
<td class="r Data">1.0521</td>
<td class="r Data">1.0576</td>
<td class="r Data">1.0705</td>
<td class="r Data" nowrap>-0.09746</td>
<td class="r Data">0.00038</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">26</th>
<td class="r Data">26</td>
<td class="r Data">1.1121</td>
<td class="r Data">1.1601</td>
<td class="r Data">1.2781</td>
<td class="r Data"> 0.10669</td>
<td class="r Data">0.00051</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">27</th>
<td class="r Data">27</td>
<td class="r Data">1.0490</td>
<td class="r Data">1.0263</td>
<td class="r Data">1.0236</td>
<td class="r Data" nowrap>-0.14032</td>
<td class="r Data">0.00100</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">28</th>
<td class="r Data">28</td>
<td class="r Data">1.2291</td>
<td class="r Data">1.2258</td>
<td class="r Data">1.0134</td>
<td class="r Data"> 0.51066</td>
<td class="r Data">0.01495</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">29</th>
<td class="r Data">29</td>
<td class="r Data">0.9069</td>
<td class="r Data">0.9234</td>
<td class="r Data">1.1653</td>
<td class="r Data" nowrap>-0.70269</td>
<td class="r Data">0.03190</td>
<td class="l Data">No</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">30</th>
<td class="r Data">30</td>
<td class="r Data">1.3101</td>
<td class="r Data">1.3086</td>
<td class="r Data">1.2255</td>
<td class="r Data"> 0.79073</td>
<td class="r Data">0.04543</td>
<td class="l Data">No</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
</div>
<div class="branch">
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX7"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Analysis of Variance (ANOVA)for AUC0-T AUC0-INF Cmax </td>
</tr>
</table><br>
<div class="c ProcTitle">The GLM Procedure</div>
<p>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Class Levels">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="3" scope="colgroup">Class Level Information</th>
</tr>
<tr>
<th class="l b Header" scope="col">Class</th>
<th class="r b Header" scope="col">Levels</th>
<th class="l b Header" scope="col">Values</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Subject</th>
<td class="r Data">30</td>
<td class="l Data">1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">2</td>
<td class="l Data">1 2</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Per</th>
<td class="r Data">2</td>
<td class="l Data">1 2</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">2</td>
<td class="l Data">1 2</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX8"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Number of Observations">
<colgroup>
<col>
<col>
</colgroup>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Number of Observations Read</th>
<td class="r Data">60</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Number of Observations Used</th>
<td class="r Data">60</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX9"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Analysis of Variance (ANOVA)for AUC0-T AUC0-INF Cmax </td>
</tr>
</table><br>
<div class="c ProcTitle">The GLM Procedure</div>
<div class="c ProcTitle"> </div>
<div class="l ProcTitle">Dependent Variable: AUC0_T </div>
<p>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Overall ANOVA">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Sum of Squares</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Model</th>
<td class="r Data">31</td>
<td class="r Data">2.65922359</td>
<td class="r Data">0.08578141</td>
<td class="r Data">2.20</td>
<td class="r Data">0.0188</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Error</th>
<td class="r Data">28</td>
<td class="r Data">1.08944078</td>
<td class="r Data">0.03890860</td>
<td class="r Data"> </td>
<td class="r Data"> </td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Corrected Total</th>
<td class="r Data">59</td>
<td class="r Data">3.74866437</td>
<td class="r Data"> </td>
<td class="r Data"> </td>
<td class="r Data"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX10"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Fit Statistics">
<colgroup>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="r b Header" scope="col">R-Square</th>
<th class="r b Header" scope="col">Coeff Var</th>
<th class="r b Header" scope="col">Root MSE</th>
<th class="r b Header" scope="col">AUC0_T Mean</th>
</tr>
</thead>
<tbody>
<tr>
<td class="r Data">0.709379</td>
<td class="r Data">6.584329</td>
<td class="r Data">0.197253</td>
<td class="r Data">2.995789</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX11"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Type I Model ANOVA">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Type I SS</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">1</td>
<td class="r Data">0.00012241</td>
<td class="r Data">0.00012241</td>
<td class="r Data">0.00</td>
<td class="r Data">0.9557</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Per</th>
<td class="r Data">1</td>
<td class="r Data">0.03165406</td>
<td class="r Data">0.03165406</td>
<td class="r Data">0.81</td>
<td class="r Data">0.3748</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">1</td>
<td class="r Data">0.73998261</td>
<td class="r Data">0.73998261</td>
<td class="r Data">19.02</td>
<td class="r Data">0.0002</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Subject*Sequence</th>
<td class="r Data">28</td>
<td class="r Data">1.88746451</td>
<td class="r Data">0.06740945</td>
<td class="r Data">1.73</td>
<td class="r Data">0.0760</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX12"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Type III Model ANOVA">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Type III SS</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">1</td>
<td class="r Data">0.00012241</td>
<td class="r Data">0.00012241</td>
<td class="r Data">0.00</td>
<td class="r Data">0.9557</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Per</th>
<td class="r Data">1</td>
<td class="r Data">0.03165406</td>
<td class="r Data">0.03165406</td>
<td class="r Data">0.81</td>
<td class="r Data">0.3748</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">1</td>
<td class="r Data">0.73998261</td>
<td class="r Data">0.73998261</td>
<td class="r Data">19.02</td>
<td class="r Data">0.0002</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Subject*Sequence</th>
<td class="r Data">28</td>
<td class="r Data">1.88746451</td>
<td class="r Data">0.06740945</td>
<td class="r Data">1.73</td>
<td class="r Data">0.0760</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX13"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Type III Tests with Error = Type III Subject*Sequence SS">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="6" scope="colgroup">Tests of Hypotheses Using the Type III MS for Subject*Sequence as an Error Term</th>
</tr>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Type III SS</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">1</td>
<td class="r Data">0.73998261</td>
<td class="r Data">0.73998261</td>
<td class="r Data">10.98</td>
<td class="r Data">0.0026</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX14"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Analysis of Variance (ANOVA)for AUC0-T AUC0-INF Cmax </td>
</tr>
</table><br>
<div class="c ProcTitle">The GLM Procedure</div>
<div class="c ProcTitle"> </div>
<div class="l ProcTitle">Dependent Variable: AUC0_INF </div>
<p>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Overall ANOVA">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Sum of Squares</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Model</th>
<td class="r Data">31</td>
<td class="r Data">2.50943838</td>
<td class="r Data">0.08094963</td>
<td class="r Data">2.25</td>
<td class="r Data">0.0167</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Error</th>
<td class="r Data">28</td>
<td class="r Data">1.00905876</td>
<td class="r Data">0.03603781</td>
<td class="r Data"> </td>
<td class="r Data"> </td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Corrected Total</th>
<td class="r Data">59</td>
<td class="r Data">3.51849714</td>
<td class="r Data"> </td>
<td class="r Data"> </td>
<td class="r Data"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX15"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Fit Statistics">
<colgroup>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="r b Header" scope="col">R-Square</th>
<th class="r b Header" scope="col">Coeff Var</th>
<th class="r b Header" scope="col">Root MSE</th>
<th class="r b Header" scope="col">AUC0_INF Mean</th>
</tr>
</thead>
<tbody>
<tr>
<td class="r Data">0.713213</td>
<td class="r Data">6.273145</td>
<td class="r Data">0.189836</td>
<td class="r Data">3.026174</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX16"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Type I Model ANOVA">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Type I SS</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">1</td>
<td class="r Data">0.00056665</td>
<td class="r Data">0.00056665</td>
<td class="r Data">0.02</td>
<td class="r Data">0.9011</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Per</th>
<td class="r Data">1</td>
<td class="r Data">0.02715348</td>
<td class="r Data">0.02715348</td>
<td class="r Data">0.75</td>
<td class="r Data">0.3928</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">1</td>
<td class="r Data">0.69730046</td>
<td class="r Data">0.69730046</td>
<td class="r Data">19.35</td>
<td class="r Data">0.0001</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Subject*Sequence</th>
<td class="r Data">28</td>
<td class="r Data">1.78441779</td>
<td class="r Data">0.06372921</td>
<td class="r Data">1.77</td>
<td class="r Data">0.0688</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX17"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Type III Model ANOVA">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Type III SS</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">1</td>
<td class="r Data">0.00056665</td>
<td class="r Data">0.00056665</td>
<td class="r Data">0.02</td>
<td class="r Data">0.9011</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Per</th>
<td class="r Data">1</td>
<td class="r Data">0.02715348</td>
<td class="r Data">0.02715348</td>
<td class="r Data">0.75</td>
<td class="r Data">0.3928</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">1</td>
<td class="r Data">0.69730046</td>
<td class="r Data">0.69730046</td>
<td class="r Data">19.35</td>
<td class="r Data">0.0001</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Subject*Sequence</th>
<td class="r Data">28</td>
<td class="r Data">1.78441779</td>
<td class="r Data">0.06372921</td>
<td class="r Data">1.77</td>
<td class="r Data">0.0688</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX18"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Type III Tests with Error = Type III Subject*Sequence SS">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="6" scope="colgroup">Tests of Hypotheses Using the Type III MS for Subject*Sequence as an Error Term</th>
</tr>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Type III SS</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">1</td>
<td class="r Data">0.69730046</td>
<td class="r Data">0.69730046</td>
<td class="r Data">10.94</td>
<td class="r Data">0.0026</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX19"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Analysis of Variance (ANOVA)for AUC0-T AUC0-INF Cmax </td>
</tr>
</table><br>
<div class="c ProcTitle">The GLM Procedure</div>
<div class="c ProcTitle"> </div>
<div class="l ProcTitle">Dependent Variable: Cmax </div>
<p>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Overall ANOVA">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Sum of Squares</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Model</th>
<td class="r Data">31</td>
<td class="r Data">2.19798105</td>
<td class="r Data">0.07090261</td>
<td class="r Data">1.68</td>
<td class="r Data">0.0853</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Error</th>
<td class="r Data">28</td>
<td class="r Data">1.18396997</td>
<td class="r Data">0.04228464</td>
<td class="r Data"> </td>
<td class="r Data"> </td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Corrected Total</th>
<td class="r Data">59</td>
<td class="r Data">3.38195103</td>
<td class="r Data"> </td>
<td class="r Data"> </td>
<td class="r Data"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX20"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Fit Statistics">
<colgroup>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="r b Header" scope="col">R-Square</th>
<th class="r b Header" scope="col">Coeff Var</th>
<th class="r b Header" scope="col">Root MSE</th>
<th class="r b Header" scope="col">Cmax Mean</th>
</tr>
</thead>
<tbody>
<tr>
<td class="r Data">0.649915</td>
<td class="r Data">17.49338</td>
<td class="r Data">0.205632</td>
<td class="r Data">1.175486</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX21"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Type I Model ANOVA">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Type I SS</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">1</td>
<td class="r Data">0.05169225</td>
<td class="r Data">0.05169225</td>
<td class="r Data">1.22</td>
<td class="r Data">0.2783</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Per</th>
<td class="r Data">1</td>
<td class="r Data">0.01436216</td>
<td class="r Data">0.01436216</td>
<td class="r Data">0.34</td>
<td class="r Data">0.5647</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">1</td>
<td class="r Data">0.47100779</td>
<td class="r Data">0.47100779</td>
<td class="r Data">11.14</td>
<td class="r Data">0.0024</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Subject*Sequence</th>
<td class="r Data">28</td>
<td class="r Data">1.66091885</td>
<td class="r Data">0.05931853</td>
<td class="r Data">1.40</td>
<td class="r Data">0.1879</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX22"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Type III Model ANOVA">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Type III SS</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">1</td>
<td class="r Data">0.05169225</td>
<td class="r Data">0.05169225</td>
<td class="r Data">1.22</td>
<td class="r Data">0.2783</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Per</th>
<td class="r Data">1</td>
<td class="r Data">0.01436216</td>
<td class="r Data">0.01436216</td>
<td class="r Data">0.34</td>
<td class="r Data">0.5647</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">1</td>
<td class="r Data">0.47100779</td>
<td class="r Data">0.47100779</td>
<td class="r Data">11.14</td>
<td class="r Data">0.0024</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Subject*Sequence</th>
<td class="r Data">28</td>
<td class="r Data">1.66091885</td>
<td class="r Data">0.05931853</td>
<td class="r Data">1.40</td>
<td class="r Data">0.1879</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX23"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Type III Tests with Error = Type III Subject*Sequence SS">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="6" scope="colgroup">Tests of Hypotheses Using the Type III MS for Subject*Sequence as an Error Term</th>
</tr>
<tr>
<th class="l b Header" scope="col">Source</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">Type III SS</th>
<th class="r b Header" scope="col">Mean Square</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">1</td>
<td class="r Data">0.47100779</td>
<td class="r Data">0.47100779</td>
<td class="r Data">7.94</td>
<td class="r Data">0.0088</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX24"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Analysis of Variance (ANOVA)for AUC0-T AUC0-INF Cmax </td>
</tr>
</table><br>
<div class="c ProcTitle">The GLM Procedure</div>
<p>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Means">
<colgroup>
<col>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" rowspan="2" scope="col">Level of<br>Treat</th>
<th class="r b Header" rowspan="2" scope="col">N</th>
<th class="c b Header" colspan="2" scope="colgroup">AUC0_T</th>
<th class="c b Header" colspan="2" scope="colgroup">AUC0_INF</th>
<th class="c b Header" colspan="2" scope="colgroup">Cmax</th>
</tr>
<tr>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">1</th>
<th class="r Data">30</th>
<td class="r Data">2.99721767</td>
<td class="r Data">0.25051324</td>
<td class="r Data">3.02924723</td>
<td class="r Data">0.24216113</td>
<td class="r Data">1.20483802</td>
<td class="r Data">0.24634523</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">2</th>
<th class="r Data">30</th>
<td class="r Data">2.99436099</td>
<td class="r Data">0.25788211</td>
<td class="r Data">3.02310097</td>
<td class="r Data">0.25033165</td>
<td class="r Data">1.14613410</td>
<td class="r Data">0.23270268</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX25"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Means">
<colgroup>
<col>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" rowspan="2" scope="col">Level of<br>Per</th>
<th class="r b Header" rowspan="2" scope="col">N</th>
<th class="c b Header" colspan="2" scope="colgroup">AUC0_T</th>
<th class="c b Header" colspan="2" scope="colgroup">AUC0_INF</th>
<th class="c b Header" colspan="2" scope="colgroup">Cmax</th>
</tr>
<tr>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">1</th>
<th class="r Data">30</th>
<td class="r Data">2.97282049</td>
<td class="r Data">0.26786549</td>
<td class="r Data">3.00490069</td>
<td class="r Data">0.26160213</td>
<td class="r Data">1.16001450</td>
<td class="r Data">0.27846530</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">2</th>
<th class="r Data">30</th>
<td class="r Data">3.01875817</td>
<td class="r Data">0.23753073</td>
<td class="r Data">3.04744751</td>
<td class="r Data">0.22793746</td>
<td class="r Data">1.19095762</td>
<td class="r Data">0.19642004</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX26"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: Means">
<colgroup>
<col>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" rowspan="2" scope="col">Level of<br>Sequence</th>
<th class="r b Header" rowspan="2" scope="col">N</th>
<th class="c b Header" colspan="2" scope="colgroup">AUC0_T</th>
<th class="c b Header" colspan="2" scope="colgroup">AUC0_INF</th>
<th class="c b Header" colspan="2" scope="colgroup">Cmax</th>
</tr>
<tr>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Std Dev</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">1</th>
<th class="r Data">30</th>
<td class="r Data">3.10684357</td>
<td class="r Data">0.18362267</td>
<td class="r Data">3.13397797</td>
<td class="r Data">0.17495261</td>
<td class="r Data">1.26408702</td>
<td class="r Data">0.19804870</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">2</th>
<th class="r Data">30</th>
<td class="r Data">2.88473510</td>
<td class="r Data">0.26463251</td>
<td class="r Data">2.91837023</td>
<td class="r Data">0.25821353</td>
<td class="r Data">1.08688510</td>
<td class="r Data">0.24729348</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX27"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Analysis of Variance (ANOVA)for AUC0-T AUC0-INF Cmax </td>
</tr>
</table><br>
<div class="c ProcTitle">The GLM Procedure</div>
<div class="c ProcTitle">Least Squares Means</div>
<p>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: LSMeans">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" rowspan="2" scope="col">Treat</th>
<th class="r b Header" rowspan="2" scope="col">AUC0_T LSMEAN</th>
<th class="r b Header" rowspan="2" scope="col">Standard Error</th>
<th class="c b Header" scope="col">H0:LSMEAN=0</th>
<th class="c b Header" scope="col">H0:LSMean1=LSMean2</th>
</tr>
<tr>
<th class="r b Header" scope="col">Pr > |t|</th>
<th class="r b Header" scope="col">Pr > |t|</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">1</th>
<td class="r Data">2.99721767</td>
<td class="r Data">0.03601324</td>
<td class="r Data"><.0001</td>
<td class="r Data">0.9557</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">2</th>
<td class="r Data">2.99436099</td>
<td class="r Data">0.03601324</td>
<td class="r Data"><.0001</td>
<td class="r Data"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX28"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: LSMeans">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" rowspan="2" scope="col">Treat</th>
<th class="r b Header" rowspan="2" scope="col">AUC0_INF LSMEAN</th>
<th class="r b Header" rowspan="2" scope="col">Standard Error</th>
<th class="c b Header" scope="col">H0:LSMEAN=0</th>
<th class="c b Header" scope="col">H0:LSMean1=LSMean2</th>
</tr>
<tr>
<th class="r b Header" scope="col">Pr > |t|</th>
<th class="r b Header" scope="col">Pr > |t|</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">1</th>
<td class="r Data">3.02924723</td>
<td class="r Data">0.03465920</td>
<td class="r Data"><.0001</td>
<td class="r Data">0.9011</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">2</th>
<td class="r Data">3.02310097</td>
<td class="r Data">0.03465920</td>
<td class="r Data"><.0001</td>
<td class="r Data"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX29"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure GLM: LSMeans">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="l b Header" rowspan="2" scope="col">Treat</th>
<th class="r b Header" rowspan="2" scope="col">Cmax LSMEAN</th>
<th class="r b Header" rowspan="2" scope="col">Standard Error</th>
<th class="c b Header" scope="col">H0:LSMEAN=0</th>
<th class="c b Header" scope="col">H0:LSMean1=LSMean2</th>
</tr>
<tr>
<th class="r b Header" scope="col">Pr > |t|</th>
<th class="r b Header" scope="col">Pr > |t|</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">1</th>
<td class="r Data">1.20483802</td>
<td class="r Data">0.03754315</td>
<td class="r Data"><.0001</td>
<td class="r Data">0.2783</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">2</th>
<td class="r Data">1.14613410</td>
<td class="r Data">0.03754315</td>
<td class="r Data"><.0001</td>
<td class="r Data"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
</div>
<div class="branch">
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX30"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Non Parametric Analysis of Tmax </td>
</tr>
</table><br>
<div class="c ProcTitle">The Mixed Procedure</div>
<p>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Mixed: Model Information">
<colgroup>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="2" scope="colgroup">Model Information</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Data Set</th>
<td class="l Data">WORK.EE</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Dependent Variable</th>
<td class="l Data">Tmax1</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Covariance Structure</th>
<td class="l Data">Diagonal</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Estimation Method</th>
<td class="l Data">REML</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Residual Variance Method</th>
<td class="l Data">Profile</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Fixed Effects SE Method</th>
<td class="l Data">Model-Based</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Degrees of Freedom Method</th>
<td class="l Data">Residual</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX31"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Mixed: Class Level Information">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="3" scope="colgroup">Class Level Information</th>
</tr>
<tr>
<th class="l b Header" scope="col">Class</th>
<th class="r b Header" scope="col">Levels</th>
<th class="l b Header" scope="col">Values</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Subject</th>
<td class="r Data">30</td>
<td class="l Data">1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">2</td>
<td class="l Data">1 2</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Per</th>
<td class="r Data">2</td>
<td class="l Data">1 2</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">2</td>
<td class="l Data">1 2</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX32"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Mixed: Dimensions">
<colgroup>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="2" scope="colgroup">Dimensions</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Covariance Parameters</th>
<td class="r Data">1</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Columns in X</th>
<td class="r Data">7</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Columns in Z</th>
<td class="r Data">0</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Subjects</th>
<td class="r Data">1</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Max Obs Per Subject</th>
<td class="r Data">60</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX33"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Mixed: Number of Observations">
<colgroup>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="2" scope="colgroup">Number of Observations</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Number of Observations Read</th>
<td class="r Data">60</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Number of Observations Used</th>
<td class="r Data">60</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Number of Observations Not Used</th>
<td class="r Data">0</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX34"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Mixed: Covariance Parameter Estimates">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="2" scope="colgroup">Covariance Parameter Estimates</th>
</tr>
<tr>
<th class="l b Header" scope="col">Cov Parm</th>
<th class="r b Header" scope="col">Estimate</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Residual</th>
<td class="r Data">0.3868</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX35"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Mixed: Fit Statistics">
<colgroup>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="2" scope="colgroup">Fit Statistics</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">-2 Res Log Likelihood</th>
<td class="r Data">118.0</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">AIC (smaller is better)</th>
<td class="r Data">120.0</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">AICC (smaller is better)</th>
<td class="r Data">120.0</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">BIC (smaller is better)</th>
<td class="r Data">122.0</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX36"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Mixed: Type 3 Tests of Fixed Effects">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="5" scope="colgroup">Type 3 Tests of Fixed Effects</th>
</tr>
<tr>
<th class="l b Header" scope="col">Effect</th>
<th class="r b Header" scope="col">Num DF</th>
<th class="r b Header" scope="col">Den DF</th>
<th class="r b Header" scope="col">F Value</th>
<th class="r b Header" scope="col">Pr > F</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<td class="r Data">1</td>
<td class="r Data">56</td>
<td class="r Data">0.17</td>
<td class="r Data">0.6811</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Per</th>
<td class="r Data">1</td>
<td class="r Data">56</td>
<td class="r Data">0.31</td>
<td class="r Data">0.5788</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Sequence</th>
<td class="r Data">1</td>
<td class="r Data">56</td>
<td class="r Data">0.17</td>
<td class="r Data">0.6811</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX37"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Mixed: Estimates">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="9" scope="colgroup">Estimates</th>
</tr>
<tr>
<th class="l b Header" scope="col">Label</th>
<th class="r b Header" scope="col">Estimate</th>
<th class="r b Header" scope="col">Standard Error</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">t Value</th>
<th class="r b Header" scope="col">Pr > |t|</th>
<th class="r b Header" scope="col">Alpha</th>
<th class="r b Header" scope="col">Lower</th>
<th class="r b Header" scope="col">Upper</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">T vs R</th>
<td class="r Data">0.06633</td>
<td class="r Data">0.1606</td>
<td class="r Data">56</td>
<td class="r Data">0.41</td>
<td class="r Data">0.6811</td>
<td class="r Data">0.1</td>
<td class="r Data" nowrap>-0.2023</td>
<td class="r Data">0.3349</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX38"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Mixed: Least Squares Means">
<colgroup>
<col>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="10" scope="colgroup">Least Squares Means</th>
</tr>
<tr>
<th class="l b Header" scope="col">Effect</th>
<th class="l b Header" scope="col">Treat</th>
<th class="r b Header" scope="col">Estimate</th>
<th class="r b Header" scope="col">Standard Error</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">t Value</th>
<th class="r b Header" scope="col">Pr > |t|</th>
<th class="r b Header" scope="col">Alpha</th>
<th class="r b Header" scope="col">Lower</th>
<th class="r b Header" scope="col">Upper</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<th class="l Data">1</th>
<td class="r Data">2.4113</td>
<td class="r Data">0.1136</td>
<td class="r Data">56</td>
<td class="r Data">21.24</td>
<td class="r Data"><.0001</td>
<td class="r Data">0.1</td>
<td class="r Data">2.2214</td>
<td class="r Data">2.6013</td>
</tr>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<th class="l Data">2</th>
<td class="r Data">2.4777</td>
<td class="r Data">0.1136</td>
<td class="r Data">56</td>
<td class="r Data">21.82</td>
<td class="r Data"><.0001</td>
<td class="r Data">0.1</td>
<td class="r Data">2.2877</td>
<td class="r Data">2.6676</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
<a name="IDX39"></a>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Mixed: Differences of Least Squares Means">
<colgroup>
<col>
<col>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="11" scope="colgroup">Differences of Least Squares Means</th>
</tr>
<tr>
<th class="l b Header" scope="col">Effect</th>
<th class="l b Header" scope="col">Treat</th>
<th class="l b Header" scope="col">_Treat</th>
<th class="r b Header" scope="col">Estimate</th>
<th class="r b Header" scope="col">Standard Error</th>
<th class="r b Header" scope="col">DF</th>
<th class="r b Header" scope="col">t Value</th>
<th class="r b Header" scope="col">Pr > |t|</th>
<th class="r b Header" scope="col">Alpha</th>
<th class="r b Header" scope="col">Lower</th>
<th class="r b Header" scope="col">Upper</th>
</tr>
</thead>
<tbody>
<tr>
<th class="l RowHeader" scope="row">Treat</th>
<th class="l Data">1</th>
<th class="l Data">2</th>
<td class="r Data" nowrap>-0.06633</td>
<td class="r Data">0.1606</td>
<td class="r Data">56</td>
<td class="r Data" nowrap>-0.41</td>
<td class="r Data">0.6811</td>
<td class="r Data">0.1</td>
<td class="r Data" nowrap>-0.3349</td>
<td class="r Data">0.2023</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
</div>
<div class="branch">
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX40"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Schuirmann two-one sided test for AUC0-T AUC0-INF Cmax </td>
</tr>
</table><br>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Print: Data Set WORK.NEW_AA">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c Header" scope="col">Obs</th>
<th class="l Header" scope="col">PK</th>
<th class="c Header" scope="col">n</th>
<th class="c Header" scope="col">T1</th>
<th class="r Header" scope="col">P1</th>
<th class="c Header" scope="col">T2</th>
<th class="r Header" scope="col">P2</th>
<th class="c Header" scope="col">TCritV</th>
</tr>
</thead>
<tbody>
<tr>
<th class="r RowHeader" scope="row">1</th>
<td class="l Data">AUC0-T</td>
<td class="r Data">30</td>
<td class="r Data">4.43736</td>
<td class="r Data">0.0001</td>
<td class="r Data" nowrap>-4.32518</td>
<td class="r Data">0.0001</td>
<td class="r Data">1.70113</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">2</th>
<td class="l Data">AUC0-INF</td>
<td class="r Data">30</td>
<td class="r Data">4.67783</td>
<td class="r Data">0.0000</td>
<td class="r Data" nowrap>-4.42704</td>
<td class="r Data">0.0001</td>
<td class="r Data">1.70113</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">3</th>
<td class="l Data">Cmax</td>
<td class="r Data">30</td>
<td class="r Data">5.30839</td>
<td class="r Data">0.0000</td>
<td class="r Data" nowrap>-3.09707</td>
<td class="r Data">0.0022</td>
<td class="r Data">1.70113</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
</div>
<div class="branch">
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX41"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Confidence Interval and Geometric Mean Ratio for AUC0-T AUC0-INF Cmax</td>
</tr>
</table><br>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Print: Data Set WORK.NEW_PP">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c Header" scope="col">Obs</th>
<th class="l Header" scope="col">PK</th>
<th class="c Header" scope="col">N</th>
<th class="c Header" scope="col">Geometric_Mean_Ratio</th>
<th class="c Header" scope="col">Lower</th>
<th class="c Header" scope="col">UPPER</th>
<th class="c Header" scope="col">Confidence_Level</th>
<th class="c Header" scope="col">BE_Range</th>
<th class="c Header" scope="col">Assessment</th>
</tr>
</thead>
<tbody>
<tr>
<th class="r RowHeader" scope="row">1</th>
<td class="l Data">AUC0-T</td>
<td class="r Data">30</td>
<td class="r Data"> 100.286</td>
<td class="r Data">91.9631</td>
<td class="r Data">109.362</td>
<td class="r Data">90</td>
<td class="l Data" nowrap>80-125</td>
<td class="l Data">BE</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">2</th>
<td class="l Data">AUC0-INF</td>
<td class="r Data">30</td>
<td class="r Data"> 100.617</td>
<td class="r Data">92.5672</td>
<td class="r Data">109.366</td>
<td class="r Data">90</td>
<td class="l Data" nowrap>80-125</td>
<td class="l Data">BE</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">3</th>
<td class="l Data">Cmax</td>
<td class="r Data">30</td>
<td class="r Data"> 106.046</td>
<td class="r Data">96.8879</td>
<td class="r Data">116.070</td>
<td class="r Data">90</td>
<td class="l Data" nowrap>80-125</td>
<td class="l Data">BE</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
</div>
<div class="branch">
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX42"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Arithmetic Mean and Coefficient of Variation for Tmax</td>
</tr>
</table><br>
<div class="c ProcTitle">The MEANS Procedure</div>
<p>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Means: Summary statistics">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c b Header" colspan="4" scope="colgroup">Analysis Variable : Tmax1 </th>
</tr>
<tr>
<th class="r b Header" scope="col">Treat</th>
<th class="r b Header" scope="col">Mean</th>
<th class="r b Header" scope="col">Median</th>
<th class="r b Header" scope="col">Coeff of Variation</th>
</tr>
</thead>
<tbody>
<tr>
<th class="r t Data">1</th>
<td class="r Data">2.411</td>
<td class="r Data">2.330</td>
<td class="r Data">24.525</td>
</tr>
<tr>
<th class="r t Data">2</th>
<td class="r Data">2.478</td>
<td class="r Data">2.500</td>
<td class="r Data">25.643</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
</div>
<div class="branch">
</div>
<div class="branch">
</div>
<div class="branch">
</div>
<div class="branch">
</div>
<div class="branch">
</div>
<div class="branch">
</div>
<div class="branch">
<p style="page-break-after: always;"><br></p><hr size="3">
<a name="IDX43"></a>
<table class="SysTitleAndFooterContainer" width="100%" cellspacing="1" cellpadding="1" rules="none" frame="void" border="0" summary="Page Layout">
<tr>
<td class="c SystemTitle">Variability with Sample_Size and power For Pharmacokinetics Parameters AUC0-T AUC0-INF Cmax</td>
</tr>
</table><br>
<div>
<div align="center">
<table class="Table" cellspacing="1pt" cellpadding="10pt" rules="all" frame="box" border="4pt" bordercolor="#000000" summary="Procedure Print: Data Set WORK.FINAL1">
<colgroup>
<col>
</colgroup>
<colgroup>
<col>
<col>
<col>
<col>
<col>
<col>
<col>
</colgroup>
<thead>
<tr>
<th class="c Header" scope="col">Obs</th>
<th class="c Header" scope="col">N</th>
<th class="l Header" scope="col">PK</th>
<th class="r Header" scope="col">CVintra</th>
<th class="r Header" scope="col">CVinter</th>
<th class="c Header" scope="col">Intraclass_Correlation</th>
<th class="r Header" scope="col">Power</th>
<th class="c Header" scope="col">Sample_Size</th>
</tr>
</thead>
<tbody>
<tr>
<th class="r RowHeader" scope="row">1</th>
<td class="r Data">30</td>
<td class="l Data">AUC0-T</td>
<td class="r Data"> 19.919</td>
<td class="r Data"> 11.980</td>
<td class="r Data"> 0.268</td>
<td class="r Data"> 92.8261</td>
<td class="l Data">Sufficient</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">2</th>
<td class="r Data">30</td>
<td class="l Data">AUC0-INF</td>
<td class="r Data"> 19.157</td>
<td class="r Data"> 11.809</td>
<td class="r Data"> 0.278</td>
<td class="r Data"> 94.8975</td>
<td class="l Data">Sufficient</td>
</tr>
<tr>
<th class="r RowHeader" scope="row">3</th>
<td class="r Data">30</td>
<td class="l Data">Cmax</td>
<td class="r Data"> 20.781</td>
<td class="r Data"> 9.248</td>
<td class="r Data"> 0.168</td>
<td class="r Data"> 72.7879</td>
<td class="l Data">Not Suffic</td>
</tr>
</tbody>
</table>
</div>
</div>
<br>
</div>
</body>
</html>
@Ksharp is correct, someone is probably playing around with the extension name for the file and not using the correct one. Word can open HTML files though, that's always been the case, so you can save your HTML as a Word doc and/or HTML. These are not identical but I think you get the idea.
ods html path='C:\_localdata\' body='sample.rtf' style=meadow;
proc print data=sashelp.class;
run;
ods html close;
ods html file='C:\_localdata\sample.html' style=meadow;
proc print data=sashelp.class;
run;
ods html close;
Hi Reeza,
Thx a lot for the reply.
However , I run each syntax separately and i fkound the same problem which is there are differences between the WORD and HTML (HTML file table has blue titles and separated lines, while the word file doesn't)
if you check the code 1 I sent; you will find that the WORD file tables are separated by lines).
pls check the 2 codes I sent.
Thx
@MohamedYehia wrote:
Hi Reeza,
Thx a lot for the reply.
However , I run each syntax separately and i fkound the same problem which is there are differences between the WORD and HTML (HTML file table has blue titles and separated lines, while the word file doesn't)
if you check the code 1 I sent; you will find that the WORD file tables are separated by lines).
pls check the 2 codes I sent.
Thx
I am confused about what your issue is. It sounds like you have used SAS to create an HTML file and have opened it with a browser and also with WORD. You are concerned that WORD makes the file look different than the browser does. That is normal behaviour. You could probably also see differences just using different browsers.
If you want the file to always look the same then you probably want to create a PDF file instead. That is what PDF was desgned for.
There's a blob of text, but this is one example where you should probably attach a file, not a wall of text.
I'm not going to work with that.
I did mention it's not identical, but the approach is the same. Open the HTML file if you'd like and save it in Word and you'll have the identical file. Most likely that's what the person did, or some variation of the above that managed to work. Note that you can do these types of things in multiple directions, ie I showed ODS HTML, you could try the same with ODS RTF or a different tagset. They could also have used a custom tagset. There's too many ways it could have been done - why don't you ask the person who sent you the file?
1) if you try to open the html file and save it as word, it will also generate a totally different one.
2) I can't ask the one who did that because he is an outsource personnel who is earning money in return of that work, so simply he will not give me the "no how" of his work 😄 😄
3) this is my email: "Mohamed_phr@hotmail.com" if you decided to run the both source codes and I know that the source code is too large, but btw its too simple, you will just copy paste each code and then right click the file and select open with "either chrome or word"
sorry for bothering u 😉
If he's a contractor, the code he's written may be your company's IP so you should have access to it if you ask.
I wonder if this new posting is related to this thread from a few weeks ago: https://communities.sas.com/t5/ODS-and-Base-Reporting/How-to-import-ods-html-to-rtf-output/m-p/38742...
The bottom line is that if you use ODS HTML, you are making an HTML file, no matter what file extension you give the file. And if you "resave" the HTML file from inside WORD as a .doc or .docx, then you are asking WORD to convert from HTML to internal WORD format. Ever since Office 97, you have been able to open an HTML file with WORD and EXCEL, so that is something Microsoft implemented a long time ago.
The output from ODS HTML will not be the same as the output from ODS RTF.
Since I'm still not clear on what the issue is or why an HTML file is being created and then opened with WORD, I'm not sure that a "fix" is needed.
cynthia
@MohamedYehia wrote:
Hi Reeza,
Thx a lot for the reply.
However , I run each syntax separately and i fkound the same problem which is there are differences between the WORD and HTML (HTML file table has blue titles and separated lines, while the word file doesn't)
The output of ODS HTML and ODS RTF will vary in colors, line types, fonts and almost every appearance issue because the ODS destinations have different default styles if you did not include the style on the ODS statement as @Reezadid.
Please show the code you actually ran.
@MohamedYehia wrote:
if you check the code 1 I sent; you will find that the WORD file tables are separated by lines).
pls check the 2 codes I sent.
I couldn't tell where your "code 1" may have ended and your "code 2" began and I'm not going to spend much time looking through several hundred lines of HTML code to compare things.
If you do not have the source code used to generate the tables do not expect us to reverse engineer any of the options that may have been used in Proc report which could have used different Break Rbreak or other options in other procedures that generated different styles of lines. If thas is what your are attempting then have the person send you the code that generated the output. But if they used a custom style or procedure template that may not contain all of the information.
And repeat, NONE of that output was Word it was all html.
I took your two blobs of HTML, saved them to files, and then attached them as output1.txt and output2.txt. As someone mentioned earlier, this is the preferred way to share a large amount of data.
The forum software wouldn't let me attach .htm files (!!) so download the files and rename them to output1.htm and output2.htm.
The output1.htm file was created using the HTML3 destination and the "Default" style supplied by SAS.
The output2.htm file was created using the HTML4 destination and a style that is similar to "Default". I see some differences but I'm unable to tell if they are due to being created by different versions of SAS, or if someone modified the "Default" style and used it here.
Open both files using a Web browser and you will see that they have a similar, but different appearance.
Now open both files using Microsoft Word. The two files look very different when rendered by Microsoft Word. The output1.htm file looks close to what you see in the Web browser. The HTML for the output2.htm file uses CSS to control the appearance, and apparently Microsoft Word does not handle the CSS very well.
Here is some sample code that illustrates how the files might have been created:
ods html3 file='C:\temp\vince_output1.htm' style=Default;
proc means data=sashelp.class n mean median min max range;
class sex;
var age height weight;
run; quit;
ods html3 close;
ods html4 file='C:\temp\vince_output2.htm' style=Default;
proc means data=sashelp.class n mean median min max range;
class sex;
var age height weight;
run; quit;
ods html4 close;
Vince DelGobbo
SAS R&D
Hi Vince_SAS,
you can't imagine how happy I am 😄 ..... you are really my hero 😉
HTML3 is the solution .
I really appreciate your kind assistance
thx again and good luck
Yours,
M.Yehia
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