I understand that. I just haven't fulled grasped how one can test multiple joint hypotheses using slice or lsmestimate without specifying coefficients. I'm sure it is possible, but I just do not quite understand it. In one of the examples you linked, they showed: proc logistic data=uti; freq count; class diagnosis treatment/param=glm; model response = diagnosis treatment diagnosis*treatment; lsmestimate diagnosis*treatment 'A vs C complicated' 1 0 -1 / exp; run; They explain how this compares the first and third values from the lsmeans table. While I had some difficulty making the same extrapolations to other models, it seems like the harder problem is then combining terms (e.g. treatment*diagnosis AND diagnosis are > 0). Again, I'm sure that is possible, but I just haven't really gotten it using the other approaches.
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