Hi Damien, Sorry, your last comment make me confused. 1. Could you clearly describe what 0.13, 0.10 and hold=1,2 mean separately in the command below? What 0.13? 0.10? hold=1,2? I hope it will be clear for any value given for the next time if you describe for what these values stand for. Where do you get these values? parms (0.13)(0.10)/hold=1,2; 2. Is Bonferroni correction work if I randomly sampled three clinics with the three treatments per district/block? 3. The main reason I was planning to have one treatment clinic per district is information contamination; however, if it is not statistically feasible, I will randomly allocate the three treatments in three clinics which will are too far apart. 4. Should the effect size and variance be similar for the three treatments? Is it possible to use the least effect size and variance for all treatments in simulation? 5. Sorry, for the last time, what will be the sample size, precision and power if we assume 12 clusters per treatment (36 total clusters), 95%, average cluster size = 60, P1=30, P2=40, P3=50, effect size = 0.10, ICC=0.04, coefficient of variation = 0.5 and the variance = 0.4? These are under the assumption of three clinics/treatment unit per district/block and two clinics/treatment units per district/block. What will the simulation look like? 6. For which case = three clinics/treatment unit per district/block or two clinics/treatment units per district/block, does the Bonferroni correction work? Kind regards Teketo
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