sas codes for Interim analysis using o'brien-flemming method

[Uche_Okoro]

Hello,

I am trying to do an interim analysis using the o'brien-flemming method. I found these codes. However I do not know how to edit to input my own data. This seems like a macro. My data includes ID numbers, treatment group, result before and after treatment.

Thank you.

proc seqdesign altref=0.4
               pss
               stopprob
               errspend
               ;
   TwoSidedPocock:        design nstages=4 method=poc;
   TwoSidedOBrienFleming: design nstages=4 method=obf;
   samplesize model=twosamplemean(stddev=0.8 weight=2);
run;

[Norman21]

It looks like the code is taken from Example 77.3 of the online user guide here:

https://support.sas.com/documentation/cdl/en/statug/63033/HTML/default/viewer.htm#statug_seqdesign_s...

Have you tried looking at the explanation of the syntax, which can be found (for example) here?

https://support.sas.com/documentation/cdl/en/statug/63033/HTML/default/viewer.htm#statug_seqdesign_s...