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Soontobeprofess
Calcite | Level 5

I am a graduate student and I need to analyze area under the curve for the following data set (individual subject), can someone give me a simple code for it please. I will do this for every subject and after that I will run the ANOVAs pre and post, thank you very much. 

Min    Glucose 

-775
073
273
1278
28106
43110
58102
73101
8899
10388
11882
13382
14880
16379
17876
19374
20975
22474
24478
3 REPLIES 3
Ksharp
Super User
data have;
input Min    Glucose ;
cards;
-7	75
0	73
2	73
12	78
28	106
43	110
58	102
73	101
88	99
103	88
118	82
133	82
148	80
163	79
178	76
193	74
209	75
224	74
244	78
;

data temp;
 set have;
 delta=dif(min);
 high=mean(lag(Glucose),Glucose);
run;
proc sql noprint;
select sum(delta*high) into : auc from temp;
quit;


proc sgplot data=have;
series x=min y=glucose;
inset "AUC=&auc";
run;
Soontobeprofess
Calcite | Level 5

Dear community

 

 Thank you so much for your help. The code runs fine. I have two more questions:

 

The first, I forgot to ask, I need to calculate AUC from minute 0 to 240 only. 

 

The second one, in case on missing data (in rare cases, some of the glucose sensors didn't catch the  last hour of glucose readings), how can i modify the code to compensate for it? Thank you very much. 

 

P

Ksharp
Super User
For first question:
Add a filter condition .

data temp;
set have(where=(min between 0 and 240));
..........


For second question, you can impute the missing value with lag value . Like :
data temp;
set have(where=(min between 0 and 240));
retain new_glucose ;
if not missing(glucose ) then new_glucose =glucose ;
drop glucose ;
run;

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