Those are not SAS data sets.  If you have the proper PC files software you can treat each XLSX as a data library where sheets and ranges are members. Something like this. libname CRF1 excel 'D:\Users\patience.tubie\SAS Data Sets\CRF1.xlsx'; proc datasets library=CRF1;      run;      quit; I don't know if that is exactly correct (RTM).  Bottom line is you don't have SAS data sets. ... View more