Hello,
I am not an expert in frailty models (for sure not in practice), but here's some info.
The PHREG procedure in SAS implements the penalized likelihood method for the gamma and log-normal frailty models. SAS/STAT 15.3 User's Guide The PHREG Procedure The Frailty Model https://go.documentation.sas.com/doc/en/pgmsascdc/9.4_3.5/statug/statug_phreg_details16.htm
Paper 1492-2014 Introduction to Frailty Models John Amrhein, McDougall Scientific Ltd. https://support.sas.com/resources/papers/proceedings14/1492-2014.pdf
If you encounter recurrent disease episodes in patients, then this paper may be of interest: Analysis of Correlated Recurrent and Terminal Events Data in SAS® Li Lu(1), Chenwei Liu(2) 1 The EMMES Corporation, Rockville, MD 2 Core Genotyping Facility, Division of Cancer Epidemiology and Genetics, Advanced Technology Program, SAIC Frederick, Inc., NCI-Frederick, Frederick, MD https://www.lexjansen.com/nesug/nesug08/sa/sa16.pdf
BR, Koen
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