At a very -basic- level, my Pharma students tell me that they use the following methods to produce the tables and graphs they need for clinical trial reporting:
--SAS/GRAPH with ANNOTATE
--ODS GRAPHICS with Statistical Procedures
--SAS/GRAPH SG Procedures
--SAS Macro Programs
For more information about the FDA requirements, you should look at the FDA site. In addition, if you work for a Pharmaceutical company or a CRO, it is my experience that every company has their own procedure for validating code logic and producing reports. Some companies produce tables with DATA _NULL_ and LISTING output and have a group create the RTF or PDF files required by the FDA. Some companies use ODS RTF or ODS PDF.
As previously explained the standards are voluminous and the implementation of the standards is equally voluminous.