Programming the statistical procedures from SAS

two sample proportion equivalence test

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Contributor
Posts: 25

two sample proportion equivalence test

Hello:

   I want to do a sample size calculation for a two proportion equivalence test to show two drugs are not different. According to this link, 

http://support.sas.com/kb/50/700.html

SAS does not implement this in proc power. 

 

Does anyone know a work around? Do I need to implement it myself?

 

Thanks,

Peter

 

Respected Advisor
Posts: 2,655

Re: two sample proportion equivalence test

The usage note you refer to is from 2013, and there have been improvements to PROC POWER.  In the SAS/STAT14.1 documentation located here:

 

http://support.sas.com/documentation/cdl/en/statug/68162/HTML/default/viewer.htm#statug_power_syntax...

 

there is substantial material related to two sample equivalence and inferiority/superiority testing.

 

Steve Denham

SAS Employee
Posts: 51

Re: two sample proportion equivalence test

I think this paper will give you the answer:

 

Paper SAS1911-2015

Equivalence and Noninferiority Testing Using SAS/STAT® Software

John Castelloe and Donna Watts, SAS Institute Inc.

http://support.sas.com/resources/papers/proceedings15/SAS1911-2015.pdf

 

The whole paper (23 pages) is worth reading but you can directly go to

PROPORTIONS, RISK DIFFERENCES, AND RELATIVE RISKS (page 9)

and

Power and Sample Size Analysis for Proportions, Risk Differences, and Relative Risks (page 11)

 

Good luck,

Koen

Super User
Posts: 9,779

Re: two sample proportion equivalence test

Or you could data simulation:

http://blogs.sas.com/content/iml/2013/06/05/simulation-power-curve.html

http://blogs.sas.com/content/iml/2013/05/30/simulation-power.html


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