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ybz12003
Rhodochrosite | Level 12

Assume we would like to investigate if there is a suitable biomarker to detect the progressing of disease A.   We select five biomarkers and 30 participants.  We record the different periods of those biomarker concentrations, which are 0 month, 6 months, 12 months and 24 months.  And the golden standard diagnosis is X-ray ( Yes/No). 

To find the best biomarker, what statistical model I should use?  Multilinear regression?  How to write the SAS code?  Please help.  Thanks.

1 ACCEPTED SOLUTION

Accepted Solutions
Reeza
Super User

The GLM repeated measures example in the documentation is close to what you need. 

 

You can't use PROC REG because you have a repeated measures design, which requires PROC GLM or PROC MIXED. 

 

Full methodological support is a bit outside the scope of this forum IMO. 

If you're not sure what methods to be using consider taking the FREE SAS statistical course. 

See bottom right hand corner of the page. 

http://support.sas.com/training/tutorial/

 

FYI 30 participants is not enough to determine conclusive results. 

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1 REPLY 1
Reeza
Super User

The GLM repeated measures example in the documentation is close to what you need. 

 

You can't use PROC REG because you have a repeated measures design, which requires PROC GLM or PROC MIXED. 

 

Full methodological support is a bit outside the scope of this forum IMO. 

If you're not sure what methods to be using consider taking the FREE SAS statistical course. 

See bottom right hand corner of the page. 

http://support.sas.com/training/tutorial/

 

FYI 30 participants is not enough to determine conclusive results. 

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