04-25-2016 10:43 PM
So I am trying to replicate this statement in SAS (basically to come up with the 300 patients part), but I can't seem to figure out how:
60% of the patients will be considered adherent, 300 patients will allow an AUC of 0.80 to be estimated with an accuracy (i.e. half width of the 95% confidence interval) of 0.049
04-26-2016 09:57 AM
Some things to consider. AUC is likely lognormally distributed. Iget something like this from:
proc power; OneSampleMeans test = t Dist = LogNormal Alpha = 0.05 Sides = 2 Mean = 0.8 NullMean = 0.79 CV = 0.06125 Power = 0.8 NTotal = . ;
Where I got the CV as .049/0.8.
This may just be coincidental, though.