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Lund's Test for Outlier Analysis

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Occasional Contributor
Posts: 6

Lund's Test for Outlier Analysis

Dear all

Can you help me to make Lund Test for Outlier Analysis in Ratios to be used in bioequivalence studies, var AUC & Cmax

For Example:

ObsSubjectRatio for AUCTRatio for AUC00Ratio for CmaxLundPrescottOutlier
111.409881.315430.911762.730853.27961No
220.953850.947830.968861.000643.27961No

Best Regards

Ahmed

Occasional Contributor
Posts: 6

Re: Lund's Test for Outlier Analysis

Dear all

Can you help me to make Lund Test for Outlier Analysis in Ratios to be used in bioequivalence studies, var AUC & Cmax

For Example:

ObsSubjectRatio for AUCTRatio for AUC00Ratio for CmaxLundPrescottOutlier
111.409881.315430.911762.730853.27961No
220.953850.947830.968861.000643.27961No

Best Regards

Ahmed

SAS Super FREQ
Posts: 3,542

Re: Lund's Test for Outlier Analysis

Try posting this to the Community for SAS Statistical Procedures

I am not familiar with Lund's Test. Can you post a reference?  I found this discussion

http://forum.bebac.at/mix_entry.php?id=2144

Many years ago james Handsfield at the CDC developed a SAS macro for detecting outliers. If you want to see what he did, his paper is at http://www2.sas.com/proceedings/sugi23/Posters/p197.pdf

Occasional Contributor
Posts: 6

Re: Lund's Test for Outlier Analysis

Thank you Rick

Occasional Contributor
Posts: 6

Re: Lund's Test for Outlier Analysis

I found this code:

Proc glm outstat=Lund;

class Subject Treat Seq Period;

MODEL Log_AUCT Log_AUCinf Log_Cmax=seq subject(seq) Treat period;

lsmeans Treat/stderr; Estimate 'test-ref' Treat -1 1;

Output out=Lund P=PRED R=RESID stdr=eresid STUDENT=STDRESID;

run;

Best Regards

Ahmed

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