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Lund's Test for Outlier Analysis

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Occasional Contributor
Posts: 6

Lund's Test for Outlier Analysis

Dear all

Can you help me to make Lund Test for Outlier Analysis in Ratios to be used in bioequivalence studies, var AUC & Cmax

For Example:

ObsSubjectRatio for AUCTRatio for AUC00Ratio for CmaxLundPrescottOutlier
111.409881.315430.911762.730853.27961No
220.953850.947830.968861.000643.27961No

Best Regards

Ahmed

Occasional Contributor
Posts: 6

Re: Lund's Test for Outlier Analysis

Posted in reply to ahmedazab88

Dear all

Can you help me to make Lund Test for Outlier Analysis in Ratios to be used in bioequivalence studies, var AUC & Cmax

For Example:

ObsSubjectRatio for AUCTRatio for AUC00Ratio for CmaxLundPrescottOutlier
111.409881.315430.911762.730853.27961No
220.953850.947830.968861.000643.27961No

Best Regards

Ahmed

SAS Super FREQ
Posts: 4,240

Re: Lund's Test for Outlier Analysis

Posted in reply to ahmedazab88

Try posting this to the Community for SAS Statistical Procedures

I am not familiar with Lund's Test. Can you post a reference?  I found this discussion

http://forum.bebac.at/mix_entry.php?id=2144

Many years ago james Handsfield at the CDC developed a SAS macro for detecting outliers. If you want to see what he did, his paper is at http://www2.sas.com/proceedings/sugi23/Posters/p197.pdf

Occasional Contributor
Posts: 6

Re: Lund's Test for Outlier Analysis

Thank you Rick

Occasional Contributor
Posts: 6

Re: Lund's Test for Outlier Analysis

Posted in reply to ahmedazab88

I found this code:

Proc glm outstat=Lund;

class Subject Treat Seq Period;

MODEL Log_AUCT Log_AUCinf Log_Cmax=seq subject(seq) Treat period;

lsmeans Treat/stderr; Estimate 'test-ref' Treat -1 1;

Output out=Lund P=PRED R=RESID stdr=eresid STUDENT=STDRESID;

run;

Best Regards

Ahmed

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