Without actually knowing, my guess is: no, you can't.
What are you trying to do?
From what kind of SAS session do you want to execute an EG project?
Why can't you just export the project as SAS code, or register it as a Stored Process?
You can script SAS Enterprise Guide to open/run a project or process flow, or do a number of other actions. All of this is "invisible" - no UI is presented when you script EG. To script EG you need to use a scripting language such as VB Script or PowerShell, which you can launch using the X statement or SYSTASK function in SAS. Note that you will need SAS Enterprise Guide to be installed on the machine that is running the script.
Chris I tried to view the api help file after downloading, do I need to place it somewhere special, when I load it the contents come up but the html page says it is a invalid address when i click one of the documents in the tabel of contents.