For those working in an academic environment, you might want to take a look at SAS OnDemand for Academics -- a new offering that uses SAS Enterprise Guide to connect to a SAS-hosted compute environment.
I read the blog referenced in Chris' post. It just raises the question of when EG 4.1 will be upgraded to support Vista in regular production since it supports Vista in the SAS-on-demand. Some of my students with new computers are having to go back and back-fit with XP.
Doc, I saw your comment on the blog post and responded with the official company line about Vista support.
But we're all friends here in this forum, right? So I can tell you a little more about what I know without implying any additional official support?
I can say I have heard anecdotes from adventurous folks running EG 4.1 on this platform. What problems must they overcome? (I post these notes for those who are curious -- please don't take this information as a statement of official support. All such official statements are at http://support.sas.com/techsup/pcn/vista.html.)
1. System requirements: EG 4.1 requires .NET 1.1. On Vista the EG install doesn't detect its absence, so it must be installed manually.
2. Installation: Vista's user account control can sure get in the way. Those entertaining PC/Mac commercials ("Cancel or allow?") don't exaggerate much.
3. Some UI oddities -- strange UI appearance for some tasks -- but if you have the latest EG 4.1 hotfix, this shouldn't be an issue. Note that EG hotfixes are good for production EG, not for SAS Learning Edition.
That's what I know. There may be additional issues that I don't know about; I'm speaking from our experience of creating a Vista-ready application for the SAS OnDemand environment and our work for EG 4.2, which has full support for Vista.