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Combination Studies to Assess Deviations from Additivity: 3D Surface

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Combination Studies to Assess Deviations from Additivity: 3D Surface

I am interested in analyzing the response of two drugs in combination (full factorial design). I will represent the response as fold above expected additivity (A+B / A alone + B alone). The output that most interests me would be the volume under the 3D response surface. Does anyone know how to go about doing this in JMP? I have been attempting this with surface plots but can not get the surface visualization...I am in need of a model. Any suggestions?

Community Manager
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Re: Combination Studies to Assess Deviations from Additivity: 3D Surface

While you might learn some good drug-development methodology advice from this group, you should check out the JMP Community for the best advice about how to use the tools there -- the JMP experts all hang out in that community.

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