topic Re: Glimmix for longitudinal binary outcome in Statistical Procedures https://communities.sas.com/t5/Statistical-Procedures/Glimmix-for-longitudinal-binary-outcome/m-p/117328#M6158 <HTML><HEAD></HEAD><BODY><P>YES!&nbsp; You will probably need to include some kind of error structure in the random statement, and the choices will depend on the spacing of the time points and the amount of data you have to fit the various structures.&nbsp; For examples, look at Stroup's <EM>Generalized Linear Mixed Models</EM>.</P><P></P><P>Steve Denham</P></BODY></HTML> Mon, 21 Oct 2013 11:56:09 GMT SteveDenham 2013-10-21T11:56:09Z Glimmix for longitudinal binary outcome https://communities.sas.com/t5/Statistical-Procedures/Glimmix-for-longitudinal-binary-outcome/m-p/117327#M6157 <HTML><HEAD></HEAD><BODY><P>Previously I have been using GLIMMIX with the LOGIT link to look at the effect of covariates and time on a disease diagnosis (0,1). Subject outcomes were recorded at 4 time points.&nbsp; The results looked reasonable.&nbsp; Most recently, I recoded the outcome so that if a subject had the disease at any time point they would also have the disease at later time points.&nbsp; The output looks terrible- the estimates are outrageously large.&nbsp; Could this be due to the correlations between timepoints?</P><P>-G</P></BODY></HTML> Sat, 19 Oct 2013 17:23:45 GMT https://communities.sas.com/t5/Statistical-Procedures/Glimmix-for-longitudinal-binary-outcome/m-p/117327#M6157 gaucho 2013-10-19T17:23:45Z Re: Glimmix for longitudinal binary outcome https://communities.sas.com/t5/Statistical-Procedures/Glimmix-for-longitudinal-binary-outcome/m-p/117328#M6158 <HTML><HEAD></HEAD><BODY><P>YES!&nbsp; You will probably need to include some kind of error structure in the random statement, and the choices will depend on the spacing of the time points and the amount of data you have to fit the various structures.&nbsp; For examples, look at Stroup's <EM>Generalized Linear Mixed Models</EM>.</P><P></P><P>Steve Denham</P></BODY></HTML> Mon, 21 Oct 2013 11:56:09 GMT https://communities.sas.com/t5/Statistical-Procedures/Glimmix-for-longitudinal-binary-outcome/m-p/117328#M6158 SteveDenham 2013-10-21T11:56:09Z