topic Interraction in Statistical Procedures https://communities.sas.com/t5/Statistical-Procedures/Interraction/m-p/779399#M38256 <P>Am working on this practice learning model: I have a data that can be used to estimate the effects of two genes on cancer incidence.&nbsp; Assume these data were obtained from a large prospective cohort study.&nbsp; It can be assumed that the sample was taken from a genetically homogenous population and thus confounding is not an issue. How can I present the evidence for interaction as suggested by Knol and VandeWeele (2012) in table form. First, I thought about creating a dummy variable in sas but I don't know the code for interaction for a dichotomous variable.</P><P>This is my sample data:</P><TABLE border="0" cellspacing="0" cellpadding="0"><TBODY><TR><TD>ID</TD><TD>GeneA</TD><TD>GeneB</TD><TD>Cancer</TD></TR><TR><TD>1</TD><TD>0</TD><TD>1</TD><TD>1</TD></TR><TR><TD>2</TD><TD>0</TD><TD>0</TD><TD>1</TD></TR><TR><TD>3</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>4</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>5</TD><TD>0</TD><TD>1</TD><TD>0</TD></TR><TR><TD>6</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>7</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>8</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>9</TD><TD>0</TD><TD>0</TD><TD>1</TD></TR><TR><TD>10</TD><TD>0</TD><TD>1</TD><TD>0</TD></TR><TR><TD>11</TD><TD>1</TD><TD>0</TD><TD>0</TD></TR><TR><TD>12</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>13</TD><TD>0</TD><TD>1</TD><TD>0</TD></TR><TR><TD>14</TD><TD>1</TD><TD>0</TD><TD>0</TD></TR><TR><TD>15</TD><TD>1</TD><TD>0</TD><TD>0</TD></TR><TR><TD>16</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>17</TD><TD>0</TD><TD>1</TD><TD>0</TD></TR><TR><TD>18</TD><TD>0</TD><TD>1</TD><TD>0</TD></TR><TR><TD>19</TD><TD>1</TD><TD>1</TD><TD>1</TD></TR></TBODY></TABLE> Tue, 09 Nov 2021 19:19:56 GMT CathyVI 2021-11-09T19:19:56Z Interraction https://communities.sas.com/t5/Statistical-Procedures/Interraction/m-p/779399#M38256 <P>Am working on this practice learning model: I have a data that can be used to estimate the effects of two genes on cancer incidence.&nbsp; Assume these data were obtained from a large prospective cohort study.&nbsp; It can be assumed that the sample was taken from a genetically homogenous population and thus confounding is not an issue. How can I present the evidence for interaction as suggested by Knol and VandeWeele (2012) in table form. First, I thought about creating a dummy variable in sas but I don't know the code for interaction for a dichotomous variable.</P><P>This is my sample data:</P><TABLE border="0" cellspacing="0" cellpadding="0"><TBODY><TR><TD>ID</TD><TD>GeneA</TD><TD>GeneB</TD><TD>Cancer</TD></TR><TR><TD>1</TD><TD>0</TD><TD>1</TD><TD>1</TD></TR><TR><TD>2</TD><TD>0</TD><TD>0</TD><TD>1</TD></TR><TR><TD>3</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>4</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>5</TD><TD>0</TD><TD>1</TD><TD>0</TD></TR><TR><TD>6</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>7</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>8</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>9</TD><TD>0</TD><TD>0</TD><TD>1</TD></TR><TR><TD>10</TD><TD>0</TD><TD>1</TD><TD>0</TD></TR><TR><TD>11</TD><TD>1</TD><TD>0</TD><TD>0</TD></TR><TR><TD>12</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>13</TD><TD>0</TD><TD>1</TD><TD>0</TD></TR><TR><TD>14</TD><TD>1</TD><TD>0</TD><TD>0</TD></TR><TR><TD>15</TD><TD>1</TD><TD>0</TD><TD>0</TD></TR><TR><TD>16</TD><TD>0</TD><TD>0</TD><TD>0</TD></TR><TR><TD>17</TD><TD>0</TD><TD>1</TD><TD>0</TD></TR><TR><TD>18</TD><TD>0</TD><TD>1</TD><TD>0</TD></TR><TR><TD>19</TD><TD>1</TD><TD>1</TD><TD>1</TD></TR></TBODY></TABLE> Tue, 09 Nov 2021 19:19:56 GMT https://communities.sas.com/t5/Statistical-Procedures/Interraction/m-p/779399#M38256 CathyVI 2021-11-09T19:19:56Z Re: Interraction https://communities.sas.com/t5/Statistical-Procedures/Interraction/m-p/779401#M38257 <P>Interactions in a modeling procedure are indicated with an asterisk. For example:<BR />class genea geneb;<BR />model cancer = genea geneb genea*geneb;</P> Tue, 09 Nov 2021 19:38:16 GMT https://communities.sas.com/t5/Statistical-Procedures/Interraction/m-p/779401#M38257 StatDave 2021-11-09T19:38:16Z