https://communities.sas.com/t5/Statistical-Procedures/PROC-GLM-Estimate-statement/m-p/751336#M36534 <P>See <A href="http://support.sas.com/kb/24447" target="_self">this note</A> that describes how values are determined for models involving interactions. Pay particular attention to the Introduction which tells you to avoid using the ESTIMATE and CONTRAST statements when the equivalent can much more easily be done with statements like LSMEANS, SLICE or LSMESTIMATE can be used. Many examples are provided in this note and in other notes that you can find at support.sas.com.</P> Wed, 30 Jun 2021 18:40:45 GMT StatDave 2021-06-30T18:40:45Z https://communities.sas.com/t5/Statistical-Procedures/PROC-GLM-Estimate-statement/m-p/751331#M36533 <P>When reading paper "<A href="https://www.lexjansen.com/pharmasug/2011/SAS/PharmaSUG-2011-SAS-SP01.pdf&quot;" target="_blank">https://www.lexjansen.com/pharmasug/2011/SAS/PharmaSUG-2011-SAS-SP01.pdf"</A></P><P><span class="lia-inline-image-display-wrapper lia-image-align-inline" image-alt="yw2757_0-1625077902484.png" style="width: 400px;"><img src="https://communities.sas.com/t5/image/serverpage/image-id/60864iFE7DE778B42863CC/image-size/medium?v=v2&amp;px=400" role="button" title="yw2757_0-1625077902484.png" alt="yw2757_0-1625077902484.png" /></span></P><P>&nbsp;</P><P>I am confused about the following highlighted part.</P><P>How to set these numbers? For instance, "mean of drug 1 is the same as the mean of drug 2 for disease 2" ?</P><P><span class="lia-inline-image-display-wrapper lia-image-align-inline" image-alt="yw2757_1-1625077951380.png" style="width: 400px;"><img src="https://communities.sas.com/t5/image/serverpage/image-id/60865i098B264508D65885/image-size/medium?v=v2&amp;px=400" role="button" title="yw2757_1-1625077951380.png" alt="yw2757_1-1625077951380.png" /></span></P><P>&nbsp;</P><P>Any way to understand this step?</P><P>&nbsp;</P><P>Thank you!</P><P>&nbsp;</P><P>&nbsp;</P> Wed, 30 Jun 2021 18:33:59 GMT https://communities.sas.com/t5/Statistical-Procedures/PROC-GLM-Estimate-statement/m-p/751331#M36533 yw2757 2021-06-30T18:33:59Z https://communities.sas.com/t5/Statistical-Procedures/PROC-GLM-Estimate-statement/m-p/751336#M36534 <P>See <A href="http://support.sas.com/kb/24447" target="_self">this note</A> that describes how values are determined for models involving interactions. Pay particular attention to the Introduction which tells you to avoid using the ESTIMATE and CONTRAST statements when the equivalent can much more easily be done with statements like LSMEANS, SLICE or LSMESTIMATE can be used. Many examples are provided in this note and in other notes that you can find at support.sas.com.</P> Wed, 30 Jun 2021 18:40:45 GMT https://communities.sas.com/t5/Statistical-Procedures/PROC-GLM-Estimate-statement/m-p/751336#M36534 StatDave 2021-06-30T18:40:45Z