How do I compare two hazard ratios across exposure groups in proc phreg?

mkit8 — Sun, 05 Apr 2020 23:08:31 GMT

Hello,

Is there a way to see if there is a significant difference in the hazard ratios between age groups? (see table below or attached pdf). For example, I want to know if there is a significant difference in the HR for sex between 20-49 and 50+ year olds. And the same thing for my Race variable.

See below for the code I used to obtain these values as well).

proc sort data=new2
out=new3;
by age_recode_with_1_year_olds;

proc phreg data = new3;
class sex (ref='Male') RaceandoriginrecodeNHWNHBNHAIA (ref='Non-Hispanic White')
   Summary_stage_2000_1998 (ref='Localized')Primary_Site_labeled (ref='Proximal Colon') Grade (ref='Grade I')
   Yost_quintile_registry_based (ref='Group 5');
model Survival_months*SEERcausespecificdeathclassifi(0,8) = age_recode_with_1_year_olds sex RaceandoriginrecodeNHWNHBNHAIA Summary_stage_2000_1998 Primary_Site_labeled Grade
   Yost_quintile_registry_based / rl;
by age_recode_with_1_year_olds;
hazardratio age_recode_with_1_year_olds / DIFF=ALL;
run;

Re: How do I compare two hazard ratios across exposure groups in proc phreg?

SteveDenham — Mon, 06 Apr 2020 15:40:38 GMT

Just going off of the documentation, I think you need two HAZARDRATIO statements. Try this:

hazardratio sex/diff=ALL;
hazardratio RaceandoriginrecodeNHNWNHBNHAIA/diff=ALL;

SteveDenham

topic Re: How do I compare two hazard ratios across exposure groups in proc phreg? in Statistical Procedures

How do I compare two hazard ratios across exposure groups in proc phreg?

Re: How do I compare two hazard ratios across exposure groups in proc phreg?