topic Re: Event Rate by Cox regression in Statistical Procedures

Event Rate by Cox regression

AndreyMyslivets — Sat, 11 Aug 2018 11:10:01 GMT

Hello all!

Could you please help me with the following question:

I need to create the following table (this is example from CDISC😞

Following SAS code presented in the document:

PROC PHREG DATA=ADTTE;

MODEL AVAL*CNSR (1 2 3) = TRTPN AGEGR1N SEXN
/ ALPHA=0.05;
RUN;

I can't find event rate information at the output, could you please help me with it?

Which SAS-code should be used for Event Rate evaluation at day 168 (I higlite it using red color in the table)?

Thanks in advance,

Best Regards,

Andrey

Re: Event Rate by Cox regression

Reeza — Sat, 11 Aug 2018 12:17:23 GMT

Depending on context you're likely looking for the survival or failure rate at a specific time that you should be able to get from the output. Try an OUTPUT statement and see the output data will have what you want.

https://documentation.sas.com/?docsetId=statug&docsetVersion=14.3&docsetTarget=statug_phreg_syntax18.htm&locale=en

However, if you want to account for the other variables you'll likely want a baseline survival given certain conditions. See the example in the docs titled 'Survival Curves' which has an example you can follow.

Re: Event Rate by Cox regression

AndreyMyslivets — Sun, 12 Aug 2018 15:11:33 GMT

Thank you, Reeza!

Now I realize, that the event rate in the table is the output from PROC LIFETEST with statement "survival" and not from PROC PGREG procedure.

The line with method = "Cox Regression Model" mislead me, now I see the footnote "Based on the Kaplan-Meier estimates".

Andrey

Re: Event Rate by Cox regression

Reeza — Sun, 12 Aug 2018 23:23:21 GMT

KM doesn't account for covariates.