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    <title>topic Incremental Area Under Curve (iAUC) Calculation in Statistical Procedures</title>
    <link>https://communities.sas.com/t5/Statistical-Procedures/Incremental-Area-Under-Curve-iAUC-Calculation/m-p/466084#M24257</link>
    <description>&lt;P&gt;Hi,&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;I am unfamiliar with SAS and trying to calculate the incremental area under the curve. I normally use SPSS and have been unable to find syntax to do so using that program. I did, however, find the below guide that offers syntax to calculate AUC by three different approaches here:&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;&lt;A href="https://www.lexjansen.com/wuss/2004/posters/c_post_the_sas_calculations_.pdf" target="_blank"&gt;https://www.lexjansen.com/wuss/2004/posters/c_post_the_sas_calculations_.pdf&lt;/A&gt;&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;The method I am particularly keen to use is the "positive incremental area under the curve" one. I have downloaded SAS and am managing to successfully calculate the total AUC using the&amp;nbsp;example data and code in the link above.&amp;nbsp;I am, however, struggling to get it to work using the&amp;nbsp;code required for the alternative methods such as iAUC&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;I'd be very grateful if anyone could paste the code as it should be entered into SAS to determine the iAUC. I have also pasted a sample of&amp;nbsp;the data from my study (left column is time in minutes, right column is glucose concentration in response to a standardised meal) that is representative of what I'd like to calculate iAUC on if helpful:&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;TABLE border="0" cellspacing="0" cellpadding="0"&gt;&lt;TBODY&gt;&lt;TR&gt;&lt;TD&gt;0&lt;/TD&gt;&lt;TD&gt;4.746&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;15&lt;/TD&gt;&lt;TD&gt;6.688&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;30&lt;/TD&gt;&lt;TD&gt;7.053&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;45&lt;/TD&gt;&lt;TD&gt;6.953&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;60&lt;/TD&gt;&lt;TD&gt;5.483&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;90&lt;/TD&gt;&lt;TD&gt;4.654&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;120&lt;/TD&gt;&lt;TD&gt;4.532&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;180&lt;/TD&gt;&lt;TD&gt;4.455&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;240&lt;/TD&gt;&lt;TD&gt;4.393&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;300&lt;/TD&gt;&lt;TD&gt;4.295&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;360&lt;/TD&gt;&lt;TD&gt;4.621&lt;/TD&gt;&lt;/TR&gt;&lt;/TBODY&gt;&lt;/TABLE&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;Any pointers would be much appreciated and apologies if this is very basic.&amp;nbsp;&lt;/P&gt;&lt;P&gt;&lt;BR /&gt;BW,&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;Niall&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;</description>
    <pubDate>Wed, 30 May 2018 15:14:54 GMT</pubDate>
    <dc:creator>njdempster</dc:creator>
    <dc:date>2018-05-30T15:14:54Z</dc:date>
    <item>
      <title>Incremental Area Under Curve (iAUC) Calculation</title>
      <link>https://communities.sas.com/t5/Statistical-Procedures/Incremental-Area-Under-Curve-iAUC-Calculation/m-p/466084#M24257</link>
      <description>&lt;P&gt;Hi,&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;I am unfamiliar with SAS and trying to calculate the incremental area under the curve. I normally use SPSS and have been unable to find syntax to do so using that program. I did, however, find the below guide that offers syntax to calculate AUC by three different approaches here:&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;&lt;A href="https://www.lexjansen.com/wuss/2004/posters/c_post_the_sas_calculations_.pdf" target="_blank"&gt;https://www.lexjansen.com/wuss/2004/posters/c_post_the_sas_calculations_.pdf&lt;/A&gt;&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;The method I am particularly keen to use is the "positive incremental area under the curve" one. I have downloaded SAS and am managing to successfully calculate the total AUC using the&amp;nbsp;example data and code in the link above.&amp;nbsp;I am, however, struggling to get it to work using the&amp;nbsp;code required for the alternative methods such as iAUC&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;I'd be very grateful if anyone could paste the code as it should be entered into SAS to determine the iAUC. I have also pasted a sample of&amp;nbsp;the data from my study (left column is time in minutes, right column is glucose concentration in response to a standardised meal) that is representative of what I'd like to calculate iAUC on if helpful:&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;TABLE border="0" cellspacing="0" cellpadding="0"&gt;&lt;TBODY&gt;&lt;TR&gt;&lt;TD&gt;0&lt;/TD&gt;&lt;TD&gt;4.746&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;15&lt;/TD&gt;&lt;TD&gt;6.688&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;30&lt;/TD&gt;&lt;TD&gt;7.053&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;45&lt;/TD&gt;&lt;TD&gt;6.953&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;60&lt;/TD&gt;&lt;TD&gt;5.483&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;90&lt;/TD&gt;&lt;TD&gt;4.654&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;120&lt;/TD&gt;&lt;TD&gt;4.532&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;180&lt;/TD&gt;&lt;TD&gt;4.455&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;240&lt;/TD&gt;&lt;TD&gt;4.393&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;300&lt;/TD&gt;&lt;TD&gt;4.295&lt;/TD&gt;&lt;/TR&gt;&lt;TR&gt;&lt;TD&gt;360&lt;/TD&gt;&lt;TD&gt;4.621&lt;/TD&gt;&lt;/TR&gt;&lt;/TBODY&gt;&lt;/TABLE&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;Any pointers would be much appreciated and apologies if this is very basic.&amp;nbsp;&lt;/P&gt;&lt;P&gt;&lt;BR /&gt;BW,&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;&lt;P&gt;Niall&lt;/P&gt;&lt;P&gt;&amp;nbsp;&lt;/P&gt;</description>
      <pubDate>Wed, 30 May 2018 15:14:54 GMT</pubDate>
      <guid>https://communities.sas.com/t5/Statistical-Procedures/Incremental-Area-Under-Curve-iAUC-Calculation/m-p/466084#M24257</guid>
      <dc:creator>njdempster</dc:creator>
      <dc:date>2018-05-30T15:14:54Z</dc:date>
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