topic Instrumental variable and Cox proportional hazards model in SAS Procedures

Instrumental variable and Cox proportional hazards model

Descartes — Sat, 20 Dec 2014 04:31:13 GMT

Dear all,

I want to use an instrumental variable in survival analysis, and I think the PROC SYSLIN is only for linear or logistic regression? Is there command specifically for Cox proportional hazards model?

I am thinking to use below method, is it correct? Thanks for your help!

PROC LOGISTIC DATA= data1;

MODEL GRP = Distance;

OUTPUT OUT = data2

PREDICTED=IV_grp;

RUN;

PROC PHREG DATA =data2;

CLASS AGE RACE INCOME EDUCATION / PARAM=REF REF=First ;

MODEL TIME*Status(0) = IV_grp AGE RACE INCOME EDUCATION ;

RUN;

Re: Instrumental variable and Cox proportional hazards model

SteveDenham — Mon, 22 Dec 2014 18:28:34 GMT

I think you may want to include the additional variables (AGE RACE INCOME EDUCATION) in the PROC LOGISTIC fit, as distances may cluster somewhat for these variables.

Steve Denham

Re: Instrumental variable and Cox proportional hazards model

Descartes — Tue, 23 Dec 2014 17:47:32 GMT

Thanks Steve! Is there any test I can do on this instrumental variable?

Re: Instrumental variable and Cox proportional hazards model

SteveDenham — Tue, 30 Dec 2014 14:24:55 GMT

Well, there should be a Wald chi-square test in the output for PROC PHREG for this variable.

Steve Denham