topic Need some insight into the significance issue in SAS Procedures https://communities.sas.com/t5/SAS-Procedures/Need-some-insight-into-the-significance-issue/m-p/115567#M31948 <HTML><HEAD></HEAD><BODY><P>I have a factorial design. When I perform the overall main effects and the interaction effects tests, all of them are NOT significant. However, when I use the slice option in PROC MIXED, this is, I asses the effect of one factor at each level of the other factor,&nbsp; one of these test comes out highly significant. How should I take this? just disregard in view of the overall test non-significance ? or consider further using some adjustment for multiple comparisons?</P><P>I am attaching an image of the SAS output for you to see. Notice the overall test output above and the slice effects on the bottom.</P><P>Thanks a lot for any lights you can provide!</P><P>Juan </P></BODY></HTML> Fri, 21 Jun 2013 18:15:10 GMT juan 2013-06-21T18:15:10Z Need some insight into the significance issue https://communities.sas.com/t5/SAS-Procedures/Need-some-insight-into-the-significance-issue/m-p/115567#M31948 <HTML><HEAD></HEAD><BODY><P>I have a factorial design. When I perform the overall main effects and the interaction effects tests, all of them are NOT significant. However, when I use the slice option in PROC MIXED, this is, I asses the effect of one factor at each level of the other factor,&nbsp; one of these test comes out highly significant. How should I take this? just disregard in view of the overall test non-significance ? or consider further using some adjustment for multiple comparisons?</P><P>I am attaching an image of the SAS output for you to see. Notice the overall test output above and the slice effects on the bottom.</P><P>Thanks a lot for any lights you can provide!</P><P>Juan </P></BODY></HTML> Fri, 21 Jun 2013 18:15:10 GMT https://communities.sas.com/t5/SAS-Procedures/Need-some-insight-into-the-significance-issue/m-p/115567#M31948 juan 2013-06-21T18:15:10Z