https://communities.sas.com/t5/SAS-Health-and-Life-Sciences/sample-size-calculation/m-p/5773#M511 Hi, <BR /> <BR /> I am doing the sample size calculation for a clinical trial with three arms. The data analysis will use MANCOVA or MANOVA. There are two primary outcome variables interested. Can somebody give me some information on how to calculate the sample size for this if we know the effect size between the arms.<BR /> <BR /> Thanks. Ruby Sun, 02 Dec 2007 17:14:39 GMT deleted_user 2007-12-02T17:14:39Z https://communities.sas.com/t5/SAS-Health-and-Life-Sciences/sample-size-calculation/m-p/5773#M511 Hi, <BR /> <BR /> I am doing the sample size calculation for a clinical trial with three arms. The data analysis will use MANCOVA or MANOVA. There are two primary outcome variables interested. Can somebody give me some information on how to calculate the sample size for this if we know the effect size between the arms.<BR /> <BR /> Thanks. Ruby Sun, 02 Dec 2007 17:14:39 GMT https://communities.sas.com/t5/SAS-Health-and-Life-Sciences/sample-size-calculation/m-p/5773#M511 deleted_user 2007-12-02T17:14:39Z https://communities.sas.com/t5/SAS-Health-and-Life-Sciences/sample-size-calculation/m-p/5774#M512 Hi:<BR /> Possibly these books/papers will be useful:<BR /> <A href="http://support.sas.com/rnd/app/papers/linearmodelspower.pdf" target="_blank">http://support.sas.com/rnd/app/papers/linearmodelspower.pdf</A><BR /> <BR /> A Step-By-Step Approach to Using SAS for Univariate and Multivariate Statistics<BR /> By Norm O'Rourke, Larry Hatcher, Edward J. Stepanski <BR /> Published 2005 SAS Publishing <BR /> ISBN 1590474171 <BR /> <BR /> cynthia Sun, 02 Dec 2007 20:06:48 GMT https://communities.sas.com/t5/SAS-Health-and-Life-Sciences/sample-size-calculation/m-p/5774#M512 Cynthia_sas 2007-12-02T20:06:48Z