topic Combination Studies to Assess Deviations from Additivity: 3D Surface in SAS Health and Life Sciences https://communities.sas.com/t5/SAS-Health-and-Life-Sciences/Combination-Studies-to-Assess-Deviations-from-Additivity-3D/m-p/263485#M2438 <P>I am interested in analyzing the response of two drugs in combination&nbsp;(full factorial design). I will represent the response as fold above expected additivity (A+B / A alone + B alone). The output that most interests me&nbsp;would be the volume under the 3D response surface. Does anyone know how to go about doing this in JMP? I have been attempting this with surface plots&nbsp;but can not get the surface visualization...I am in need of a model. Any suggestions?</P> Wed, 13 Apr 2016 12:27:19 GMT 2112rob2112 2016-04-13T12:27:19Z Combination Studies to Assess Deviations from Additivity: 3D Surface https://communities.sas.com/t5/SAS-Health-and-Life-Sciences/Combination-Studies-to-Assess-Deviations-from-Additivity-3D/m-p/263485#M2438 <P>I am interested in analyzing the response of two drugs in combination&nbsp;(full factorial design). I will represent the response as fold above expected additivity (A+B / A alone + B alone). The output that most interests me&nbsp;would be the volume under the 3D response surface. Does anyone know how to go about doing this in JMP? I have been attempting this with surface plots&nbsp;but can not get the surface visualization...I am in need of a model. Any suggestions?</P> Wed, 13 Apr 2016 12:27:19 GMT https://communities.sas.com/t5/SAS-Health-and-Life-Sciences/Combination-Studies-to-Assess-Deviations-from-Additivity-3D/m-p/263485#M2438 2112rob2112 2016-04-13T12:27:19Z Re: Combination Studies to Assess Deviations from Additivity: 3D Surface https://communities.sas.com/t5/SAS-Health-and-Life-Sciences/Combination-Studies-to-Assess-Deviations-from-Additivity-3D/m-p/263486#M2439 <P>While you might learn some good drug-development methodology advice from this group, you should <A href="https://community.jmp.com" target="_self">check out the JMP Community</A> for the best advice about how to use the tools there -- the JMP experts all hang out in that community.</P> Wed, 13 Apr 2016 12:41:31 GMT https://communities.sas.com/t5/SAS-Health-and-Life-Sciences/Combination-Studies-to-Assess-Deviations-from-Additivity-3D/m-p/263486#M2439 ChrisHemedinger 2016-04-13T12:41:31Z