topic Re: End point variables in Clinical trails in SAS Health and Life Sciences

End point variables in Clinical trails

deleted_user — Tue, 16 Sep 2008 19:33:20 GMT

Hello, Can any body pls tell me what are the end point variables in clinical trails?

Thanks

Re: End point variables in Clinical trails

Doc_Duke — Wed, 17 Sep 2008 01:28:27 GMT

It varies by trial, but is the outcome measure in the specific aims of the protocol.

In a thrombolytic trial, it might be death; in a diabetes trial, it might be a reduction in HbA1c, etc.

Doc Muhlbaier
Duke

Re: End point variables in Clinical trails

deleted_user — Wed, 17 Sep 2008 16:01:28 GMT

Thanks Doc. That info was very helpful.
Can you pls tell me a couple of end point variables in cardio vascular therapeutic area.

Thanks

Re: End point variables in Clinical trails

Doc_Duke — Wed, 17 Sep 2008 18:07:55 GMT

For further examples of endpoints, just go to http://clinicaltrials.gov/ and look up some phama sponsored trials.

Re: End point variables in Clinical trails

deleted_user — Wed, 17 Sep 2008 21:11:36 GMT

Primary endpoint definition:
“clinical endpoint that provides evidence sufficient to fully categorize clinically the effect of a treatment that would support a regulatory claim for the treatment”
Secondary endpoint:
“additional clinical characterization of a treatment but could not, by itself, be convincing of a clinically significant treatment effect”