topic Re: calculation of risk difference in SAS Programming https://communities.sas.com/t5/SAS-Programming/calculation-of-risk-difference/m-p/953250#M372463 <P>Thanks for your reply. Do you know how data should be structured before using proc freq?</P> Wed, 11 Dec 2024 16:25:13 GMT kalbo 2024-12-11T16:25:13Z calculation of risk difference https://communities.sas.com/t5/SAS-Programming/calculation-of-risk-difference/m-p/953227#M372455 <P>Hi all, I need to add the calculated Risk Difference to listings of preferred terms for a trial. There are 2 arms: dose and placebo.</P> <P>&nbsp;</P> <P>Per FDA standards, I would like to add risk difference with 95% confidence intervals. This can be added to either the AE data set, or to the proc report.</P> <P>&nbsp;</P> <P><STRONG>prefterm&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; dose&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; placebo&nbsp; riskdifference</STRONG></P> <P>Cold&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 3&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 2</P> <P>Flu&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 2&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 1</P> <P>Headache&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 1&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 3</P> Wed, 11 Dec 2024 13:11:41 GMT https://communities.sas.com/t5/SAS-Programming/calculation-of-risk-difference/m-p/953227#M372455 kalbo 2024-12-11T13:11:41Z Re: calculation of risk difference https://communities.sas.com/t5/SAS-Programming/calculation-of-risk-difference/m-p/953231#M372459 <P>You need&nbsp;<SPAN>to specify the <STRONG>RISKDIFF</STRONG> option in <STRONG>PROC FREQ</STRONG>.</SPAN></P> <H1 class="xisDoc-title">The FREQ Procedure</H1> <DIV class="Placeholders_tabbar__2jBEC"><NAV class="TabBar_tabbar__1xNb7 navbar navbar-expand-md navbar-light" role="application"> <DIV class="navbar-collapse collapse"> <DIV class="navbar-nav">&nbsp;</DIV> </DIV> </NAV></DIV> <DIV id="statug.freq.freqriskdiff" class="aa-section"> <DIV class="xisDoc-title"> <DIV> <DIV> <H4 class="xisDoc-title">Risks and Risk Differences<BR /><A href="https://go.documentation.sas.com/doc/en/statug/15.2/statug_freq_details54.htm" target="_blank">https://go.documentation.sas.com/doc/en/statug/15.2/statug_freq_details54.htm</A></H4> <P>&nbsp;</P> <P>Ciao, Koen</P> </DIV> </DIV> </DIV> </DIV> Wed, 11 Dec 2024 13:38:35 GMT https://communities.sas.com/t5/SAS-Programming/calculation-of-risk-difference/m-p/953231#M372459 sbxkoenk 2024-12-11T13:38:35Z Re: calculation of risk difference https://communities.sas.com/t5/SAS-Programming/calculation-of-risk-difference/m-p/953250#M372463 <P>Thanks for your reply. Do you know how data should be structured before using proc freq?</P> Wed, 11 Dec 2024 16:25:13 GMT https://communities.sas.com/t5/SAS-Programming/calculation-of-risk-difference/m-p/953250#M372463 kalbo 2024-12-11T16:25:13Z Re: calculation of risk difference https://communities.sas.com/t5/SAS-Programming/calculation-of-risk-difference/m-p/953348#M372472 <P>See documentation :&nbsp;</P> <P><A href="https://go.documentation.sas.com/doc/en/statug/latest/statug_freq_details01.htm" target="_blank">SAS Help Center: Inputting Frequency Counts</A></P> <P>&nbsp;</P> <P><SPAN>PROC FREQ can use either raw data or cell count data to produce frequency and crosstabulation tables.&nbsp;</SPAN><STRONG><EM>Raw data</EM></STRONG><SPAN>, also known as case-record data, report the data as one record for each subject or sample member.&nbsp;</SPAN><STRONG><EM>Cell count data</EM></STRONG><SPAN>&nbsp;report the data as a table, listing all possible combinations of data values along with the frequency counts.</SPAN></P> <P>&nbsp;</P> <P class="xisDoc-paragraph">The statistics for contingency tables include the following:</P> <DIV class="xisDoc-listUnordered"> <UL class="xisDoc-listUnordered" type="disc"> <LI class="xisDoc-item"> <P class="xisDoc-paraSimpleFirst">chi-square tests and measures</P> </LI> <LI class="xisDoc-item"> <P class="xisDoc-paraSimpleFirst">measures of association</P> </LI> <LI class="xisDoc-item"> <P class="xisDoc-paraSimpleFirst"><STRONG>risks (binomial proportions)</STRONG> and <STRONG>risk differences</STRONG> for&nbsp;<SPAN>2 x 2 -&nbsp;</SPAN>tables<SPAN>&nbsp;</SPAN></P> </LI> <LI class="xisDoc-item"> <P class="xisDoc-paraSimpleFirst">odds ratios and <STRONG>relative risks</STRONG> for<SPAN>&nbsp;2 x 2 -&nbsp;</SPAN>tables</P> </LI> <LI class="xisDoc-item"> <P class="xisDoc-paraSimpleFirst">tests for trend</P> </LI> <LI class="xisDoc-item"> <P class="xisDoc-paraSimpleFirst">tests and measures of agreement</P> </LI> <LI class="xisDoc-item"> <P class="xisDoc-paraSimpleFirst">Cochran-Mantel-Haenszel statistics</P> </LI> </UL> </DIV> <P><SPAN>Ciao, Koen</SPAN></P> Thu, 12 Dec 2024 08:39:55 GMT https://communities.sas.com/t5/SAS-Programming/calculation-of-risk-difference/m-p/953348#M372472 sbxkoenk 2024-12-12T08:39:55Z